Chiral Resolution of Curcumol Epoxy Derivatives by Ionic Liquid [BMIm]BF4

被引：0
作者：
Guo Ping [1 ,2 ]
Liu Jianmin [2 ]
Li Xiaokun [2 ]
Yang Shulin [1 ]
Yao Qizheng [3 ]
机构：
[1] Nanjing Univ Sci & Technol, Inst Chem Technol, Nanjing 210094, Peoples R China
[2] Wenzhou Med Coll, Sch Pharm, Wenzhou 325035, Peoples R China
[3] China Pharmaceut Univ, Sch Pharm, Nanjing 210009, Peoples R China
来源：
ACTA CHIMICA SINICA | 2010年 / 68卷 / 24期
关键词：
ionic liquid; chiral resolution; curcumol; 1 0,14-epoxycurcumol;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The isomers of 10,14-epoxycurcumol derivatives were separated by the ionic liquid [BMIm]BF4, in which there is a difference in the solubility of the complexes formed with the isomers and [BMIm]BF4. The yield 22% of (10R)-10,14-epoxycurcumol (E1) with 99% ee and the yield 49% of (10S)-10,14-epoxycurcumol (E2) with 92% ee were obtained respectively in the resolution. The ionic liquid could be recovered easily and used again with the same separation effect.
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页码：2619 / 2621
页数：3
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