Self-Assembly of DNA Nanostructures Using Three-Way Junctions on Small Circular DNAs

被引：3

作者：

Wang, Meng ^{[1
]}

Afshan, Noshin ^{[1
]}

Kou, Bo ^{[2
]}

Xiao, Shou-Jun ^{[1
]}

机构：

[1] Nanjing Univ, Sch Chem & Chem Engn, State Key Lab Coordinat Chem, 163 Xianlin Ave, Nanjing 210023, Jiangsu, Peoples R China

[2] Nanjing Inst Technol, Sch Mat Sci & Engn, Jiangsu Key Lab Adv Struct Mat & Applicat Technol, Nanjing 211167, Jiangsu, Peoples R China

来源：

CHEMNANOMAT | 2017年 / 3卷 / 10期

关键词：

DNA nanostructure; grid nanostructure; honeycomb nanostructure; multi-arm DNA tile; three-way junction; DESIGN; TRIANGLES; SYMMETRY; LIGATION; LATTICES; MOTIFS;

D O I：

10.1002/cnma.201700163

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Molecular self-assembly using DNA as a structural building block has proven to be an efficient route to the construction of nanoscale objects and arrays. Using the pre-circularised DNA as the core strand of DNA motifs provides new components for the assembly of one-, two-, and three-dimensional (1D, 2D, 3D) nanostructures. We report here honeycomb-like and grid-like framework nanostructures constructed from 3-arm triangle and 4-arm square tiles with pivotal three-way junctions on small circular oligonucleotides of 32-nt and 42-nt, respectively. However the flexible three-way junction, the crowded spatial environment of the small circular DNA motifs, and the lack of rigidity in the double helix connection may reduce the possibility to grow large single crystalline DNA lattices.

引用

页码：740 / 744

页数：5

共 33 条

[1] How Small DNA Minicircles Can Be Applied to Construct DNA Nanotubes? [J].