Unclassifiable, or simply unclassified interstitial lung disease?

被引:5
作者
O'Callaghan, Marissa [1 ,2 ]
Bonella, Francesco [3 ]
McCarthy, Cormac [1 ,2 ]
机构
[1] St Vincents Univ Hosp, Dept Resp Med, Dublin 4, Ireland
[2] Univ Coll Dublin, Sch Med, Dublin 4, Ireland
[3] Ruhrlandklin Univ Hosp Essen, Dept Pneumol, Ctr Interstitial & Rare Lung Dis, Essen, Germany
关键词
interstitial pneumonia with autoimmune features; progressive-fibrosing interstitial lung disease; unclassifiable interstitial lung disease; unclassified interstitial lung disease; IDIOPATHIC PULMONARY-FIBROSIS; MUC5B PROMOTER POLYMORPHISM; GENOME-WIDE ASSOCIATION; PNEUMONIA; SUSCEPTIBILITY; ABNORMALITIES; TELOMERASE; CLASSIFICATION; PIRFENIDONE; PREVALENCE;
D O I
10.1097/MCP.0000000000000801
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Purpose of review Unclassifiable interstitial lung disease (ILD) comprises a subset of ILDs which cannot be classified according to the current diagnostic framework. This is a likely a heterogeneous group of diseases rather than a single entity and it is poorly defined and hence problematic for prognosis and therapy. Recent findings With increased treatment options for progressive fibrosing ILD it is increasingly relevant to correctly categorise ILD. This review article will summarise the definition and reasons for a diagnosis of unclassifiable ILD, the current management options and possible future approaches to improve diagnosis and differentiation within this broad subset. Finally, we will describe the implications of the labelling of unclassifiable ILD in clinical practice and research and whether the term 'unclassified' should be used, implying a less definitive diagnosis.
引用
收藏
页码:405 / 413
页数:9
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