Synthesis of multifunctional homopolymers via sequential post-polymerization reactions

Multifunctional homopolymers, homopolymers with multiple pendent functionalities, can offer unparalleled properties not possible with traditional polymers. Preparation of multifunctional homopolymers has been a challenge, but one promising approach involves sequential and selective post-polymerization modification of macromolecular precursors. Approaches considered thus far include the use of polymers that contain monomer units with masked reaction sites for successive functionalization or the use of orthogonal or chemoselective reactions. In this mini-review, we highlight recent developments in synthesis of multifunctional homopolymers via these routes and offer insight into the promise and utility of the resulting macromolecules for materials applications.