Gas-phase pyrolysis in organic synthesis: rapid green synthesis of 4-quinolinones

被引：44

作者：

Al-Awadi, Nouria A. ^{[1
]}

Abdethamid, Ismail Abdelshafy ^{[1
]}

Al-Etaibi, Alya M. ^{[1
]}

Elnagdi, Mohamed Hilmy ^{[1
]}

机构：

[1] Kuwait Univ, Fac Sci, Dept Chem, Safat 13060, Kuwait

来源：

SYNLETT | 2007年 / 14期

关键词：

meldrum's acid; pyrolysis; 4-quinolinones;

D O I：

10.1055/s-2007-985573

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Gas-phase pyrolysis of aminomethylene Meldrum's acid derivatives gave quinolinones and/or amines depending on the nature of arylamino moiety. Effect of substituent on reaction rate and nature of pyrolysis products supports the suggested intramolecular nucleophilic substitution reaction via initially formed ketene-amine interniediate.

引用

页码：2205 / 2208

页数：4

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