Identification of Enterocin NKR-5-3C, a Novel Class IIa Bacteriocin Produced by a Multiple Bacteriocin Producer, Enterococcus faecium NKR-5-3

被引：23

作者：

Himeno, Kohei ^{[1
]}

Fujita, Koji ^{[1
]}

Zendo, Takeshi ^{[1
]}

Wilaipun, Pongtep ^{[2
]}

Ishibashi, Naoki ^{[1
]}

Masuda, Yoshimitsu ^{[1
]}

Yoneyama, Fuminori ^{[1
]}

Leelawatcharamas, Vichien ^{[3
]}

Nakayama, Jiro ^{[1
]}

Sonomoto, Kenji ^{[1
,4
]}

机构：

[1] Kyushu Univ, Grad Sch, Fac Agr, Dept Biosci & Biotechnol,Higashi Ku, Fukuoka 8128581, Japan

[2] Kasetsart Univ, Dept Fishery Prod, Fac Fisheries, Bangkok 10900, Thailand

[3] Kasetsart Univ, Fac Agro Ind, Dept Biotechnol, Bangkok 10900, Thailand

[4] Kyushu Univ, Bioarchitecture Ctr, Dept Funct Metab Design, Higashi Ku, Fukuoka 8128581, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2012年 / 76卷 / 06期

基金：

日本学术振兴会;

关键词：

bacteriocin; lactic acid bacteria; Enterococcus faecium; enterocin; pediocin; ANTI-LISTERIA BACTERIOCIN; ANTIMICROBIAL PEPTIDES; GENETIC-EVIDENCE; PURIFICATION; MODE; BIOSYNTHESIS; IMMUNITY;

D O I：

10.1271/bbb.120089

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The structure of enterocin NKR-5-3C, an antilisterial bacteriocin produced by a multiple bacteriocin producer, Enterococcus faecium NKR-5-3, was determined. Enterocin NKR-5-3C is a novel class ha bacteriocin that possesses an YGNGL motif sequence and two disulfide bridges in its structure. It is encoded on gene ent53C together with an 18-amino-acid-residue double glycine leader peptide.

引用

页码：1245 / 1247

页数：3

共 27 条

[1] Mode of action, purification and amino acid sequence of plantaricin C19, an anti-Listeria bacteriocin produced by Lactobacillus plantarum C19 [J].

Atrih, A ;

Rekhif, N ;

Moir, AJG ;

Lebrihi, A ;

Lefebvre, G .

INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 2001, 68 (1-2) :93-104

[2] Biochemical and genetic characterization of enterocin A from Enterococcus faecium, a new antilisterial bacteriocin in the pediocin family of bacteriocins [J].

Aymerich, T ;

Holo, H ;

Havarstein, LS ;

Hugas, M ;

Garriga, M ;

Nes, IF .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1996, 62 (05) :1676-1682

[3] Pheromone-induced production of antimicrobial peptides in Lactobacillus [J].

Brurberg, MB ;

Nes, IF ;

Eijsink, VGH .

MOLECULAR MICROBIOLOGY, 1997, 26 (02) :347-360

[4] Biochemical and genetic evidence that Enterococcus faecium L50 produces enterocins L50A and L50B, the sec-dependent enterocin P, and a novel bacteriocin secreted without an N-terminal extension termed enterocin Q [J].

Cintas, LM ;

Casaus, P ;

Herranz, C ;

Håvarstein, LS ;

Holo, H ;

Hernández, PE ;

Nes, IF .

JOURNAL OF BACTERIOLOGY, 2000, 182 (23) :6806-6814

[5] Bacteriocins: safe, natural antimicrobials for food preservation [J].

Cleveland, J ;

Montville, TJ ;

Nes, IF ;

Chikindas, ML .

INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 2001, 71 (01) :1-20

[6] Bacteriocins: Developing innate immunity for food [J].

Cotter, PD ;

Hill, C ;

Ross, RP .

NATURE REVIEWS MICROBIOLOGY, 2005, 3 (10) :777-788

[7] Bacteriocin T8, a novel class IIa sec-dependent bacteriocin produced by Enterococcus faecium T8, isolated from vaginal secretions of children infected with human immunodeficiency virus [J].

De Kwaadsteniet, M. ;

Fraser, T. ;

Van Reenen, C. A. ;

Dicks, L. M. T. .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2006, 72 (07) :4761-4766

[8] Bacteriocin production in vancomycin-resistant and vancomycin-susceptible Enterococcus isolates of different origins [J].

del Campo, R ;

Tenorio, C ;

Jiménez-Díaz, R ;

Rubio, C ;

Gómez-Lus, R ;

Baquero, F ;

Torres, C .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2001, 45 (03) :905-912

[9] The continuing story of class IIa bacteriocins [J].

Drider, Djamel ;

Fimland, Gunnar ;

Hechard, Yann ;

McMullen, Lynn M. ;

Prevost, Herve .

MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, 2006, 70 (02) :564-+

[10] Biochemical and genetic evidence for production of enterocins A and B by Enterococcus faecium WHE 81 [J].

Ennahar, S ;

Asou, Y ;

Zendo, T ;

Sonomoto, K ;

Ishizaki, A .

INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 2001, 70 (03) :291-301

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