Seasonal effect on chemical composition and biological activities of Sonoran propolis

被引：101

作者：

Valencia, Dora ^{[2
]}

Alday, Efrain ^{[1
]}

Robles-Zepeda, Ramon ^{[1
]}

Garibay-Escobar, Adriana ^{[1
]}

Galvez-Ruiz, Juan C. ^{[1
]}

Salas-Reyes, Magali ^{[3
]}

Jimenez-Estrada, Manuel ^{[4
]}

Velazquez-Contreras, Enrique ^{[2
]}

Hernandez, Javier ^{[3
]}

Velazquez, Carlos ^{[1
]}

机构：

[1] Univ Sonora, Dept Biol Chem, Hermosillo 83000, Sonora, Mexico

[2] Univ Sonora, Dept Polymers & Mat DIPM, Hermosillo 83000, Sonora, Mexico

[3] Univ Veracruzana, Unidad Serv Apoyo Resoluc Anal, Xalapa, Veracruz, Mexico

[4] Univ Nacl Autonoma Mexico, Inst Quim, Lab Prod Nat, Mexico City 04510, DF, Mexico

来源：

FOOD CHEMISTRY | 2012年 / 131卷 / 02期

关键词：

Sonoran propolis; Seasonal effect; Antiproliferative activity; Chemical composition; BRAZILIAN GREEN PROPOLIS; PREFERENTIAL CYTOTOXICITY; ANTIBACTERIAL ACTIVITY; ANTIOXIDANT ACTIVITY; TAIWANESE PROPOLIS; SAN-JUAN; CONSTITUENTS; ORIGIN; CELLS;

D O I：

10.1016/j.foodchem.2011.08.086

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Propolis is widely used as a folk medicine and as a constituent of health foods in many parts of the world. The main purpose of this study was to evaluate the seasonal effect on the chemical composition and biological activities (antiproliferative and antioxidant activities) of Sonoran propolis (Mexico). Propolis was collected during all four seasons of the year and chemical composition, antiproliferative, and free-radical scavenging activities of collected propolis were evaluated by HPLC, MTT, and DPPH assays, respectively. The relative abundance of the main chemical constituents of propolis was similar in all propolis samples analysed. In contrast, significant differences were observed in their antiproliferative activity in the B-cell lymphoma cancer cell line M12.C3.F6. Propolis collected in the spring showed the highest inhibitory effect on the growth of cancer cells. All propolis samples had weak free-radical scavenging activity. Our results indicate that season had a significant effect on the antiproliferative properties of Sonoran propolis. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：645 / 651

页数：7

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