Recommended Nuclear Data for the Production of Selected Therapeutic Radionuclides

被引：33

作者：

Engle, J. W. ^{[1
,17
]}

Ignatyuk, A., V ^{[2
]}

Capote, R. ^{[3
]}

Carlson, B., V ^{[4
]}

Hermanne, A. ^{[5
]}

Kellett, M. A. ^{[6
]}

Kibedi, T. ^{[7
]}

Kim, G. ^{[8
]}

Kondev, F. G. ^{[9
]}

Hussain, M. ^{[10
]}

Lebeda, O. ^{[11
]}

Luca, A. ^{[12
]}

Nagai, Y. ^{[13
]}

Naik, H. ^{[14
]}

Nichols, A. L. ^{[15
]}

Nortier, F. M. ^{[1
]}

Suryanarayana, S., V ^{[14
]}

Takacs, S. ^{[16
]}

Tarkanyi, F. T. ^{[16
]}

Verpelli, M. ^{[3
]}

机构：

[1] LANL, Los Alamos, NM USA

[2] Inst Phys & Power Engn, Obninsk, Russia

[3] IAEA, NAPC Nucl Data Sect, Vienna, Austria

[4] Inst Tecnol Aeronaut, Sao Jose Dos Campos, SP, Brazil

[5] Vrije Univ Brussel, Cyclotron Dept TONA, Brussels, Belgium

[6] CEA, LIST, Lab Natl Henri Becquerel LNE LNHB, Gif Sur Yvette, France

[7] Australian Natl Univ, Canberra, ACT, Australia

[8] Kyungpook Natl Univ, Daegu, South Korea

[9] Argonne Natl Lab, Argonne, IL 60439 USA

[10] Govt Coll Univ, Lahore, Pakistan

[11] Nucl Phys Inst, Rez, Czech Republic

[12] Natl Inst Phys & Nucl Engn Horia Hulubei, Magurele, Romania

[13] Japan Atom Energy Agcy, Tokai, Ibaraki, Japan

[14] Bhabha Atom Res Ctr, Mumbai, Maharashtra, India

[15] Univ Surrey, Guildford, Surrey, England

[16] Inst Nucl Res, Debrecen, Hungary

[17] Univ Wisconsin, Madison, WI USA

来源：

NUCLEAR DATA SHEETS | 2019年 / 155卷

关键词：

SHORT-LIVED NUCLIDE; CROSS-SECTIONS; EXCITATION-FUNCTIONS; CYCLOTRON PRODUCTION; XN REACTIONS; THORIUM; PROTONS; TH-232; PARTICLE; AC-225;

D O I：

10.1016/j.nds.2019.01.003

中图分类号：

O57 [原子核物理学、高能物理学];

学科分类号：

070202 ;

摘要：

Increasing interest in the treatment of human disease by means of targeted radionuclide-based therapies requires an accurate understanding of achievable yields and quantification of realisable degrees of purity. Important studies within a more extensive Coordinated Research Project of the International Atomic Energy Agency (IAEA CRP) have included in-depth assessments and evaluations of all available measured cross-section data for ten nuclear reactions leading to the formation of Cs-131, Ba-131, Ac-225, Ra-225, Th-227, Ac-227, U-230 and( 230)Pa for various on-going and proposed therapeutic applications in nuclear medicine. Equivalent studies were also undertaken of possible reactions to produce the W-178/low-spin Ta-178m generator system that has been clinically applied in diagnosis by means of SPECT - these particular cross-section studies and recommendations are included in this paper for completeness. All available measured data have been critically reviewed and assessed to produce statistically consistent datasets. Selected datasets have been fitted by a least-squares method with Pade approximations of variable order to evaluate the production cross sections and corresponding uncertainties. New measurements have been made in some instances, and reported data have been adjusted to accommodate new nuclear decay or monitor reaction data which altered the original reported quantities adversely. Insufficient measured data are available in many cases to permit a reliable evaluation of cross sections, and these instances are discussed. Recommended therapeutic radionuclide production reaction data and their uncertainties are available on the Web page of the IAEA Nuclear Data Section at www-nds.iaea.org/radionuclides/ and also at the IAEA medical portal www-nds.iaea.org/medportal/.

引用

页码：56 / 74

页数：19

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