New C21 steroidal glycosides, cynotophyllosides M-O, from Cynanchum otophyllum

被引：4

作者：

Ma, Lie-Feng ^{[1
]}

Miao, Cun-Tan ^{[1
]}

Qian, Hao-Ying ^{[1
]}

Wang, Peng-Fei ^{[1
]}

Wang, Fa-Song ^{[2
,3
]}

Zhan, Zha-Jun ^{[1
]}

Shan, Wei-Guang ^{[1
]}

机构：

[1] Zhejiang Univ Technol, Coll Pharmaceut Sci, Hangzhou 310014, Zhejiang, Peoples R China

[2] Hubei Univ Nationalities, Key Lab Biol Resources Protect & Utilizat Hubei P, Enshi 445000, Peoples R China

[3] Hubei Univ Nationalities, Coll Chem & Environm Engn, Enshi 445000, Peoples R China

来源：

JOURNAL OF CHEMICAL RESEARCH | 2017年 / 04期

基金：

中国国家自然科学基金;

关键词：

cynotophyllosides M-O; polyhydroxypregnane glycosides; C-21; steroids; Cynanchum otophyllum; PHOSPHODIESTERASE-4; INHIBITORS; PREGNANE GLYCOSIDES; 8,12/8,20-DIEPOXY-8,14-SECOPREGNANE GLYCOSIDES; OXYPREGNANE GLYCOSIDES; AERIAL PARTS; ROOTS; CARDENOLIDE; STEMS;

D O I：

10.3184/174751917X14894997017414

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Cynotophyllosides M-O, three new polyhydroxypregnane glycosides, were obtained from the roots of Cynanchum otophyllum, together with four known compounds, deacetylmetaplexignin, sarcostion, cynotophylloside J and kidjoranin 3-O-alpha-diginopyranosyl-(1 -> 4)-beta-cymaropyranoside.Their structures were elucidated using extensive spectroscopic methods (in particular, 2D-NMR techniques) and acid-catalysed hydrolysis.

引用

页码：195 / 198

页数：4

共 50 条

[1] Three New C21 Steroidal Glycosides from Roots of Cynanchum otophyllum
Yi-bin Zhao
Yue-mao Shen
Hong-ping He
Zhi-zhi Du
Quan-zhang Mu
Xiao-jiang Hao
Chinese Herbal Medicines, 2016, (02) : 189 - 194
[2] Four new C21 steroidal glycosides from Cynanchum otophyllum Schneid
Shen, Dong-Yan
Wei, Jin-Chao
Wan, Jian-Bo
Huang, Xiao-Jun
Xiang, Cheng
Li, Bao-Cai
Zhang, Qing-Wen
Wang, Yi-Tao
Li, Peng
PHYTOCHEMISTRY LETTERS, 2014, 9 : 86 - 91
[3] C21 Steroidal Glycosides from Acidic Hydrolysate of Cynanchum otophyllum
Yi-bin Zhao
Quan-shui Fan
Gui-li Xu
Zi-liang Feng
Xiao-jiang Hao
Chinese Herbal Medicines, 2014, (04) : 319 - 323
[4] C21 steroidal glycosides with cytotoxic activities from Cynanchum otophyllum
Dong, Jinrun
Peng, Xingrong
Li, Lei
Lu, Shuangyang
Zhou, Lin
Qiu, Minghua
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 28 (09) : 1520 - 1524
[5] C21 steroidal glycosides of seven sugar residues from Cynanchum otophyllum
Zhao, Yi-Bin
He, Hong-Ping
Lu, Chun-Hua
Mu, Quan-Zhang
Shen, Yue-Mao
Hao, Xiao-Jiang
STEROIDS, 2006, 71 (11-12) : 935 - 941
[6] C21 Steroidal Saponins from Cynanchum otophyllum
Yi-bin Zhao
Yue-mao Shen
Hong-ping He
Zhi-zhi Du
Quan-zhang Mu
Xiao-jiang Hao
ChineseHerbalMedicines, 2015, 7 (03) : 273 - 278
[7] Potential neurotrophic activity and cytotoxicity of selected C21 steroidal glycosides from Cynanchum otophyllum
Jinrun Dong
Grace Gar-Lee Yue
Julia Kin-Ming Lee
Clara Bik-San Lau
Minghua Qiu
Medicinal Chemistry Research, 2020, 29 : 549 - 555
[8] Potential neurotrophic activity and cytotoxicity of selected C21 steroidal glycosides from Cynanchum otophyllum
Dong, Jinrun
Yue, Grace Gar-Lee
Lee, Julia Kin-Ming
Lau, Clara Bik-San
Qiu, Minghua
MEDICINAL CHEMISTRY RESEARCH, 2020, 29 (03) : 549 - 555
[9] C21 Steroidal Glycosides from Cynanchum wilfordii
Xiang, Wen-Juan
Ma, Lei
Hu, Li-Hong
HELVETICA CHIMICA ACTA, 2009, 92 (12) : 2659 - 2674
[10] C21 steroidal glycosides from Cynanchum taihangense
Wang, Yu-Bo
Su, Shan-Shan
Chen, Shao-Fei
Tang, Ming-Xu
Chen, Gang
Zhao, Dan
Sang, Xia-Nan
Si, Ying-Ying
Wang, Hai-Feng
Pei, Yue-Hu
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2018, 20 (03) : 263 - 269

← 1 2 3 4 5 →