Aryne generation vs. Truce-Smiles and fries rearrangements during the Kobayashi fragmentation reaction: a new bi-aryl synthesis

被引：25

作者：

Rasheed, O. K. ^{[1
]}

Hardcastle, I. R. ^{[2
]}

Raftery, J. ^{[1
]}

Quayle, P. ^{[1
]}

机构：

[1] Univ Manchester, Sch Chem, Manchester M13 9PL, Lancs, England

[2] Newcastle Univ, Sch Chem, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2015年 / 13卷 / 29期

基金：

英国工程与自然科学研究理事会;

关键词：

DIRECT ARYLATION; CYCLIZATION; MECHANISM; PHENOLS; BIARYLS;

D O I：

10.1039/c5ob01239b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of (ortho-trimethysilyl)aryl phenylsulfonates with a soluble fluoride source initiates a Truce-Smiles rearrangement leading to the formation of functionalized bi-aryls. This new carbon-carbon bond-forming reaction proceeds without recourse to transition metal catalysis, under mild reaction conditions and with good functional group compatibility.

引用

页码：8048 / 8052

页数：5