EFFECT OF CADMIUM ON THREE ANTIOXIDANT ENZYME ACTIVITIES AND LIPID PEROXIDATION IN PLANARIAN (DUGESIA JAPONICA)

被引：0

作者：

Zhang, Xiufang ^{[1
]}

Shi, Jinxuan ^{[1
]}

Wu, Tongmin ^{[1
]}

Zhang, Yaxin ^{[1
]}

Lin, Shengcheng ^{[1
]}

Tao, Yanming ^{[1
]}

Zhao, Bosheng ^{[1
]}

机构：

[1] Shandong Univ Technol, Sch Life Sci, Zibo 255049, Peoples R China

来源：

FRESENIUS ENVIRONMENTAL BULLETIN | 2011年 / 20卷 / 11期

关键词：

Planarian (Dugesia japonica); cadmium; superoxide dismutase; catalase; glutathione peroxidase; malondidehyde; LAEONEREIS-ACUTA POLYCHAETA; OXIDATIVE STRESS; CHRONIC EXPOSURE; RESPONSES; COPPER; CD; NEREIDIDAE; TOXICITY; ALUMINUM; ANNELIDA;

D O I：

暂无

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The objective of this study was to evaluate the effects of cadmium on the antioxidant responses in planarian (Dugesia japonica). The planarians D. japonica were submitted to 0, 5, and 150 mu g of Cd2+/L during a period of test of 7 days. Compared with the control, cadmium was significantly (P < 0.05) accumulated in D. japonica exposed to 150 mu g Cd2+/L. In the worms exposed to 5 and 150 mu g Cd2+/L, catalase (CAT) activity significantly decreased compared to the control ones (P < 0.05). No significant effects on superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activity were observed. Malondidehyde (MDA) level was significantly increased following exposure to 150 mu g Cd2+/L compared with the control (P < 0.05). Thus, Cadmium could augment MDA level and interfere with the catalase of the planarian D. japonica. Results showed that CAT, rather than SOD and GSH-Px, might be a susceptible antioxidant enzyme in the metabolic detoxification processes in adult planarian D. japonica.

引用

页码：2920 / 2926

页数：7

共 38 条

[1] Response of antioxidant system of freshwater fish Oreochromis niloticus to acute and chronic metal (Cd, Cu, Cr, Zn, Fe) exposures [J].

Atli, Guluzar ;

Canli, Mustafa .

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2010, 73 (08) :1884-1889

[2] Antioxidant enzyme activities and lipid peroxidation in the freshwater cladoceran Daphnia magna exposed to redox cycling compounds [J].

Barata, C ;

Varo, I ;

Navarro, JC ;

Arun, S ;

Porte, C .

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, 2005, 140 (02) :175-186

[3] Cadmium-induced antioxidant defense mechanism in freshwater teleost Oreochromis mossambicus (Tilapia) [J].

Basha, PS ;

Rani, AU .

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2003, 56 (02) :218-221

[4]

Beauchamp C., 1971, ANAL BIOCHEM, V44, P276, DOI DOI 10.1016/0003-2697(71)90370-8

[5]

BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3

[6] Toxic effects of aluminium, chromium and cadmium in intact and regenerating freshwater planarians [J].

Calevro, F ;

Filippi, C ;

Deri, P ;

Albertosi, C ;

Batistoni, R .

CHEMOSPHERE, 1998, 37 (04) :651-659

[7] Enzyme activity alteration by cadmium administration to rats: The possibility of iron involvement in lipid peroxidation [J].

Casalino, E ;

Sblano, C ;

Landriscina, C .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1997, 346 (02) :171-179

[8] Cadmium inhibits neurogenesis in zebrafish embryonic brain development [J].

Chow, Elly Suk Hen ;

Hui, Michelle Nga Yu ;

Lin, Chun Chi ;

Cheng, Shuk Han .

AQUATIC TOXICOLOGY, 2008, 87 (03) :157-169

[9]

CMEP (China Ministry of Environmental Protection State Oceanic Administration), 2002, PEOPL REP CHIN NAT S

[10] The effect of cadmium on antioxidant responses and the susceptibility to oxidative stress in the hydrothermal vent mussel Bathymodiolus azoricus [J].

Company, R ;

Serafim, A ;

Cosson, R ;

Camus, L ;

Shillito, B ;

Fiala-Médioni, A ;

Bebianno, MJ .

MARINE BIOLOGY, 2006, 148 (04) :817-825

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