INTRODUCTION The objective of this study was to examine the clinical outcome of single-level lumbar artificial disc replacement (ADR) compared to that of transforaminal lumbar interbody fusion (TLIF) for the treatment of symptomatic degenerative disc disease (DDD) in an Asian population. METHODS This was a retrospective review of 74 patients who had surgery performed for discogenic lower backs that involved only the L4/5 and L5/S1 levels. All the patients had lumbar DDD without radiculopathy or spondylolithesis, and concordant pain with discogram at the pathological level. The patients were divided into two groups - those who underwent ADR and those who underwent TLIF. RESULTS A trend suggesting that the ADR group had better perioperative outcomes (less blood loss, shorter operating time, shorter hospital stay and shorter time to ambulation) than the TLIF group was observed. However, a trend indicating that surgical-approach-related complications occurred more frequently in the ADR group than the TLIF group was also observed. The rate of revision surgery was comparable between the two groups. CONCLUSION Our findings suggest that for the treatment of discogenic lower back pain, lumbar ADR has better perioperative outcomes and a similar revision rate when compared with TLIF. However, the use of ADR was associated with a higher incidence of surgical-approach-related complications. More studies with bigger cohort sizes and longer follow-up periods are needed to determine the long-term efficacy and safety of ADR in lumbar DDD.
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Tongji Univ, Sch Med, Shanghai East Hosp, Dept Spine Surg, 150 Jimo Rd, Shanghai 200120, Peoples R ChinaTongji Univ, Sch Med, Shanghai East Hosp, Dept Spine Surg, 150 Jimo Rd, Shanghai 200120, Peoples R China
Yu, Bin
Zhang, Jin
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Nanjing Med Univ, Shanghai East Hosp, Shanghai, Peoples R ChinaTongji Univ, Sch Med, Shanghai East Hosp, Dept Spine Surg, 150 Jimo Rd, Shanghai 200120, Peoples R China
Zhang, Jin
Pan, Jie
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Tongji Univ, Sch Med, Shanghai East Hosp, Dept Spine Surg, 150 Jimo Rd, Shanghai 200120, Peoples R ChinaTongji Univ, Sch Med, Shanghai East Hosp, Dept Spine Surg, 150 Jimo Rd, Shanghai 200120, Peoples R China
Pan, Jie
Wang, Yizhou
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Nanjing Med Univ, Changshu 2 Peoples Hosp, Changshu, Jiangsu, Peoples R ChinaTongji Univ, Sch Med, Shanghai East Hosp, Dept Spine Surg, 150 Jimo Rd, Shanghai 200120, Peoples R China
Wang, Yizhou
Chen, YingGao
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Shantou Cent Hosp, Dept Neurosurg, Shantou, Peoples R ChinaTongji Univ, Sch Med, Shanghai East Hosp, Dept Spine Surg, 150 Jimo Rd, Shanghai 200120, Peoples R China
Chen, YingGao
Zhao, Weidong
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Tongji Univ, Sch Med, Shanghai East Hosp, Dept Spine Surg, 150 Jimo Rd, Shanghai 200120, Peoples R ChinaTongji Univ, Sch Med, Shanghai East Hosp, Dept Spine Surg, 150 Jimo Rd, Shanghai 200120, Peoples R China
Zhao, Weidong
Wu, Desheng
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Tongji Univ, Sch Med, Shanghai East Hosp, Dept Spine Surg, 150 Jimo Rd, Shanghai 200120, Peoples R ChinaTongji Univ, Sch Med, Shanghai East Hosp, Dept Spine Surg, 150 Jimo Rd, Shanghai 200120, Peoples R China
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Chung Ang Univ Hosp, Dept Neurosurg, 102 Heukseok Ro, Seoul 06973, South KoreaChung Ang Univ Hosp, Dept Neurosurg, 102 Heukseok Ro, Seoul 06973, South Korea
Park, Seung Won
Kim, Young Baeg
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Chung Ang Univ Hosp, Dept Neurosurg, 102 Heukseok Ro, Seoul 06973, South KoreaChung Ang Univ Hosp, Dept Neurosurg, 102 Heukseok Ro, Seoul 06973, South Korea
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Cedars Sinai Med Ctr, Dept Orthopaed Surg, 444 S San Vicente Blvd, Los Angeles, CA 90048 USACedars Sinai Med Ctr, Dept Orthopaed Surg, 444 S San Vicente Blvd, Los Angeles, CA 90048 USA
Narendran, Nakul
Mikhail, Christopher M.
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Cedars Sinai Med Ctr, Dept Orthopaed Surg, 444 S San Vicente Blvd, Los Angeles, CA 90048 USACedars Sinai Med Ctr, Dept Orthopaed Surg, 444 S San Vicente Blvd, Los Angeles, CA 90048 USA
Mikhail, Christopher M.
Nilssen, Paal K.
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Cedars Sinai Med Ctr, Dept Orthopaed Surg, 444 S San Vicente Blvd, Los Angeles, CA 90048 USACedars Sinai Med Ctr, Dept Orthopaed Surg, 444 S San Vicente Blvd, Los Angeles, CA 90048 USA
Nilssen, Paal K.
Tuchman, Alexander
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Cedars Sinai Med Ctr, Dept Neurosurg, Los Angeles, CA USACedars Sinai Med Ctr, Dept Orthopaed Surg, 444 S San Vicente Blvd, Los Angeles, CA 90048 USA
Tuchman, Alexander
Skaggs, David L.
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Cedars Sinai Med Ctr, Dept Orthopaed Surg, 444 S San Vicente Blvd, Los Angeles, CA 90048 USACedars Sinai Med Ctr, Dept Orthopaed Surg, 444 S San Vicente Blvd, Los Angeles, CA 90048 USA