Time-lapse in the IVF-lab: how should we assess potential benefit?

被引：51

作者：

Armstrong, S. ^{[1
]}

Vail, A. ^{[2
]}

Mastenbroek, S. ^{[3
]}

Jordan, V. ^{[1
]}

Farquhar, C. ^{[1
]}

机构：

[1] Univ Auckland, Dept Obstet & Gynaecol, Auckland 1, New Zealand

[2] Univ Manchester, Manchester Acad Hlth Sci Ctr, Salford Royal Hosp, Ctr Biostat, Manchester, Lancs, England

[3] Univ Amsterdam, Acad Med Ctr, Ctr Reprod Med, NL-1105 AZ Amsterdam, Netherlands

来源：

HUMAN REPRODUCTION | 2015年 / 30卷 / 01期

关键词：

IVF; time-lapse; live birth; IVF outcome; embryo incubation; STANDARD INCUBATOR; CLINICAL-OUTCOMES; EMBRYO SELECTION; DESIGN; RATES;

D O I：

10.1093/humrep/deu250

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Time-lapse imaging of embryos has been widely introduced to fertility laboratories worldwide with the aim of identifying the best quality embryos to transfer that will ultimately improve IVF success rates. In this opinion paper, we explore the lack of evidence of benefit of this novel intervention, analyse the methodological flaws of current studies, offer ideal study designs that assess the various features of time-lapse imaging, and discuss forthcoming studies. In particular, we emphasize the ethical aspects of hastily adopting a costly technology without current high level evidence of improved live birth rates, safety and cost effectiveness.

引用

页码：3 / 8

页数：6

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