Progressive apraxia of speech as a sign of motor neuron disease

被引:37
作者
Duffy, Joseph R. [1 ]
Peach, Richard K.
Strand, Edythe A.
机构
[1] Mayo Clin, Dept Neurol, Div Speech Pathol, Rochester, MN 55905 USA
[2] Rush Univ, Med Ctr, Chicago, IL 60612 USA
关键词
apraxia of speech; motor neuron disease; amyotrophic lateral sclerosis;
D O I
10.1044/1058-0360(2007/025)
中图分类号
R36 [病理学]; R76 [耳鼻咽喉科学];
学科分类号
100104 ; 100213 ;
摘要
Purpose: To document and describe in detail the occurrence of apraxia of speech (AOS) in a group of individuals with a diagnosis of motor neuron disease (MND). Method: Seven individuals with MND and AOS were identified from among 80 patients with a variety of neurodegenerative diseases and AOS (J. R. Duffy, 2006). The history, presenting complaints, neurological findings, and speech-language findings were documented for each case. Results: Spastic or mixed spastic-flaccid dysarthria was present in all 7 cases. The AOS was judged as worse than the dysarthria in 4 cases. Nonverbal oral apraxia was eventually present in all cases. Aphasia was present in 2 cases and equivocally present in another 2. Dementia was present in 1 case and equivocally present in 2. Conclusions: AOS can occur in MND, typically also with dysarthria, but not invariably with aphasia or other cognitive deficits. Thus, a diagnosis of MND does not preclude the presence of AOS. More importantly, MND should be a diagnostic consideration when AOS is a prominent sign of degenerative disease.
引用
收藏
页码:198 / 208
页数:11
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