The biotransformation of some clovanes by Botrytis cinerea

被引：35
作者：
Collado, IG
Hanson, JR
Macías-Sánchez, AJ
Mobbs, D
机构：
[1] Univ Cadiz, Fac Ciencias, Dept Quim Organ, Cadiz 11510, Spain
[2] Univ Sussex, Sch Chem Phys & Environm Sci, Brighton BN1 9QJ, E Sussex, England
来源：
JOURNAL OF NATURAL PRODUCTS | 1998年 / 61卷 / 11期
关键词：
D O I：
10.1021/np9801054
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
The metabolism of the fungistatic agent 2 beta-methoxyclovan-9 alpha-ol (2) by the fungus Botrytis cinerea has been investigated. Biotransformation of compound 2 yielded compounds 3-5, 7, and 9. The major metabolites of compound 2 each show much reduced biological activity when compared with the parent compound. Also studied were the effects of B. cinerea on the metabolism of the related compounds 2 beta-methoxyclovan-9-one (3), 2 beta-methoxyclovan-9 beta-ol (4), and clovan-2,9-dione (6). Compounds 3, 4, 8, and 9 are described for the first time.
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页码：1348 / 1351
页数：4
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