Ligand-Free Copper-Catalyzed Arylation of Olefins by the Mizoroki-Heck Reaction

被引：26
作者：
Peng, Yong [1 ]
Chen, Jiuxi [1 ]
Ding, Jinchang [1 ,2 ]
Liu, Miaochang [1 ]
Gao, Wenxia [1 ]
Wu, Huayue [1 ]
机构：
[1] Wenzhou Univ, Coll Chem & Mat Engn, Wenzhou 325035, Peoples R China
[2] Wenzhou Vocat & Tech Coll, Wenzhou 325035, Peoples R China
来源：
SYNTHESIS-STUTTGART | 2011年 / 02期
基金：
中国国家自然科学基金;
关键词：
ligand-free; copper-catalyzed; Mizoroki-Heck reaction; cross-coupling; E-internal olefins; COUPLING REACTIONS; ARYL; EFFICIENT; COMPLEXES; BROMIDES; ALKENES; HALIDES; PEG; CO;
D O I：
10.1055/s-0030-1258338
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel ligand-free copper-catalyzed Mizoroki-Heck cross-coupling reaction of various aryl iodides with olefins has been developed. Both the solvent and the base were found to have a fundamental influence on the efficiency of the transformation in the presence of 10 mol% Cu2O, with DMF and tetramethylammonium bromide (TMAB) being the optimal solvent and base, respectively. As a result, a set of the corresponding E-internal olefins were obtained selectively in moderate to good yields.
引用
收藏
页码：213 / 216
页数：4
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