The structure elucidation of isomalyngamide K from the marine cyanobacterium Lyngbya majuscula by experimental and DFT computational methods

被引：9

作者：

Han, Bingnan ^{[2
]}

Reinscheid, Uwe M. ^{[3
]}

Gerwick, William H. ^{[4
]}

Gross, Harald ^{[1
]}

机构：

[1] Univ Bonn, Inst Pharmaceut Biol, D-53115 Bonn, Germany

[2] Zhejiang Univ, Dept Ocean Sci & Engn, Hangzhou 310028, Zhejiang, Peoples R China

[3] Max Planck Inst Biophys Chem, D-37077 Gottingen, Germany

[4] Univ Calif San Diego, Sch Pharm & Pharmaceut Sci, Ctr Marine Biotechnol & Biomed, Scripps Inst Oceanog & Skaggs, La Jolla, CA 92093 USA

来源：

JOURNAL OF MOLECULAR STRUCTURE | 2011年 / 989卷 / 1-3期

关键词：

Lyngbya majuscula; Malyngamide; Vinyl-chloride; NMR; OFT; NEW-GUINEA COLLECTION; HARE BURSATELLA-LEACHII; MALYNGAMIDES; METABOLITES; ACID;

D O I：

10.1016/j.molstruc.2011.01.012

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The 2Z-isomer of malyngamide K has been isolated along with the known compounds malyngamide C, deoxy-C and K, and characterized from a Papua New Guinea field collection of the cyanobacterium Lyngbya majuscula. The planar structure was deduced by 10 and 20 NMR spectroscopic and mass spectral data interpretation. The absolute configurations were determined on the basis of spectroscopic techniques, chemical degradation and OFT theoretical calculations. (c) 2011 Elsevier B.V. All rights reserved.

引用

页码：109 / 113

页数：5

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