Long-term outcomes of status epilepticus: A critical assessment

被引：99

作者：

Sculier, Claudine ^{[1
,2
]}

Gainza-Lein, Marina ^{[1
,3
]}

Sanchez Fernandez, Ivan ^{[1
,4
]}

Loddenkemper, Tobias ^{[1
]}

机构：

[1] Harvard Med Sch, Boston Childrens Hosp, Dept Neurol, Div Epilepsy & Clin Neurophysiol, Boston, MA USA

[2] Free Univ Brussels, Erasmus Hosp, Dept Neurol, Brussels, Belgium

[3] Univ Austral Chile, Fac Med, Valdivia, Chile

[4] Univ Barcelona, Hosp St Joan de Deu, Dept Child Neurol, Barcelona, Spain

来源：

EPILEPSIA | 2018年 / 59卷

关键词：

cognitive outcome; epilepsy; functional impairment; mortality; neurological sequelae; quality of life; CONVULSIVE STATUS EPILEPTICUS; REFRACTORY STATUS EPILEPTICUS; PEDIATRIC STATUS EPILEPTICUS; INTENSIVE-CARE; UNPROVOKED SEIZURE; EPILEPSY PATIENTS; LOW MORBIDITY; FOLLOW-UP; CHILDREN; MORTALITY;

D O I：

10.1111/epi.14515

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We reviewed 37 studies reporting long-term outcomes after a status epilepticus (SE) episode in pediatric and adult populations. Study design, length of follow-up, outcome measures, domains investigated (mortality, SE recurrence, subsequent epilepsy, cognitive outcome, functional outcome, or quality of life), and predictors of long-term outcomes are summarized. Despite heterogeneity in the design of prior studies, overall risk of poor long-term outcome after SE is high in both children and adults. Etiology is the main determinant of outcome, and the effect of age or SE duration is often difficult to distinguish from the underlying cause. The effect of the treatment on long-term outcome after SE is still unknown.

引用

页码：155 / 169

页数：15

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