An efficient synthesis of furan-3(2H)-imine scaffold from alkynones

被引：2

作者：

Rasras, Anas J. ^{[1
]}

Shehadi, Ihsan A. ^{[2
]}

Younes, Eyad A. ^{[3
]}

Jaradat, Da'san M. M. ^{[1
]}

AlQawasmeh, Raed A. ^{[2
]}

机构：

[1] Al Balqa Appl Univ, Fac Sci, Dept Chem, POB 19117, Al Salt, Jordan

[2] Univ Sharjah, Coll Sci, Dept Chem, Pure & Appl Chem Res Grp, POB 27272, Sharjah, U Arab Emirates

[3] Hashemite Univ, Fac Sci, Dept Chem, POB 330127, Zarqa 13133, Jordan

来源：

ROYAL SOCIETY OPEN SCIENCE | 2021年 / 8卷 / 11期

关键词：

efficient; synthesis; furan-3(2H)-imine; scaffold; alkynones; authors; ANTIBACTERIAL ACTIVITIES; COUPLING-CYCLIZATION; 2,3-ALLENAMIDES; HYBRIDS;

D O I：

10.1098/rsos.211145

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A novel efficient method to generate spiro furan-3(2H)-imine derivatives is established by the reaction between the alpha,beta-unsaturated ketones and aniline derivatives. The reaction involves 1,4- addition of aniline followed by the subsequent intramolecular cyclization mediated by tertiary alcohol to produce the furan-3(2H)-imine. All the synthesized compounds are characterized using nuclear magnetic resonance and high-resolution mass spectrometry (HRMS).

引用

页数：10

共 28 条

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