Guideline-Concordant Versus Discordant Antimicrobial Therapy in Patients With Community-Onset Complicated Intra-abdominal Infections

被引:4
作者
Huang, Lori L. [1 ,2 ]
Van Schooneveld, Trevor C. [3 ,4 ]
Huang, Robert D. [3 ,5 ]
Olsen, Keith M. [2 ]
Rupp, Mark E. [3 ,4 ]
Gross, Alan E. [2 ,3 ,6 ,7 ,8 ]
机构
[1] Vet Affairs Med Ctr, Patient Care Serv, Ann Arbor, MI USA
[2] Univ Nebraska Med Ctr, Coll Pharm, Omaha, NE USA
[3] Univ Nebraska Med Ctr, Coll Med, Omaha, NE USA
[4] Nebraska Med, Dept Infect Control & Epidemiol, Omaha, NE USA
[5] Univ Michigan, Emergency Med, Ann Arbor, MI 48109 USA
[6] Univ Illinois, Coll Pharm, Dept Pharm Practice, Chicago, IL USA
[7] Univ Illinois Hosp, Chicago, IL USA
[8] Hlth Sci Syst, Chicago, IL USA
关键词
DISEASES SOCIETY; MANAGEMENT; ADULTS; FAILURE; SEPSIS; RISK;
D O I
10.1017/ice.2016.64
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Overall IDSA/SIS intra-abdominal infection guideline compliance was not associated with improved outcomes; however, there was a longer time to active therapy (P = .024) and higher mortality (P = .077) if empiric therapy was too narrow per guidelines. These findings support the need for the implementation of customized institutional guidelines adapted from the IDSA/SIS guidelines.
引用
收藏
页码:855 / 858
页数:4
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