Practical considerations in enhancing LC-MS sensitivity for therapeutic protein bioanalysis

被引：4

作者：

Zhou, Shaolian ^{[1
]}

Vazvaei, Faye ^{[2
]}

Ferrari, Luca ^{[1
]}

Qu, Jun ^{[3
,4
]}

机构：

[1] Roche Innovat Ctr Basel, Roche Pharmaceut Res & Early Dev, Basel, Switzerland

[2] Roche Innovat Ctr New York, Roche Pharmaceut Res & Early Dev, New York, NY 10016 USA

[3] Univ Buffalo State Univ New York, Sch Pharm & Pharmaceut Sci, Dept Pharmaceut Sci, Buffalo, NY 14214 USA

[4] New York State Ctr Excellence Bioinformat & Life, Buffalo, NY 14203 USA

来源：

BIOANALYSIS | 2017年 / 9卷 / 18期

关键词：

LC-MS; protein bioanalysis; sensitivity; signature peptide; ORTHOGONAL ARRAY OPTIMIZATION; MASS-SPECTROMETRY; IN-DEPTH; QUANTIFICATION; PEPTIDES; ACCURATE; QUANTITATION; ANTIBODIES; LC/MS; SCALE;

D O I：

10.4155/bio-2017-4982

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

页码：1353 / 1356

页数：4

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