Determination of regulatory ionophore coccidiostat residues in feedstuffs at carry-over levels by liquid chromatography-mass spectrometry

被引：8

作者：

Annunziata, Loredana ^{[1
]}

Visciano, Pierina ^{[2
]}

Stramenga, Arianna ^{[3
]}

Colagrande, Maria Novella ^{[1
]}

Campana, Guido ^{[1
]}

Scortichini, Giampiero ^{[3
]}

Migliorati, Giacomo ^{[1
]}

Compagnone, Dario ^{[2
]}

机构：

[1] Ist Zooprofilatt Sperimentale Abruzzo & Molise G, Teramo, Italy

[2] Univ Teramo, Fac Biosci & Technol Food Agr & Environm, Teramo, Italy

[3] Ist Zooprofilatt Sperimentale Umbria & Marche, Perugia, Italy

来源：

PLOS ONE | 2017年 / 12卷 / 08期

关键词：

FEED;

D O I：

10.1371/journal.pone.0182831

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

In this study samples of feedstuffs were collected from different feed mills and animal farms located in central Italy and analyzed for ionophore coccidiostat residues at carry-over levels by liquid chromatography-mass spectrometry. Since unavoidable cross-contamination of feedstuffs may occur during their production as well as distribution and storage, the collection of samples covered all these different stages. Residues of lasalocid, monensin, salinomycin and maduramicin were detected in 32.4% of samples, both at production and storage level. The maximum content for unavoidable carry-over set by Regulation (EU) No 574/2011 was exceeded in 11.3% of samples. The variability of the results highlighted the different approach of each investigated feed business operator to avoid any cross-contamination in non-target feed. The method developed in this study can be able to detect ionophore coccidiostats at low concentrations consequent to carry-over.

引用

页数：13

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