One-pot, three-component synthesis of novel δ-sultam scaffolds via N-sulfonylation-intramolecular Michael sequences

被引：3
作者：
Ghandi, Mehdi [1 ]
Nazari, Seyed Hadi [1 ]
Bozcheloei, Abolfazl Hasani [1 ]
Sadeghzadeh, Masoud [1 ]
Kia, Reza [2 ,3 ]
机构：
[1] Univ Tehran, Sch Chem, Coll Sci, Tehran, Iran
[2] Islamic Azad Univ, Xray Crystallog Lab, Plasma Phys Res Ctr, Sci & Res Branch, Tehran, Iran
[3] Islamic Azad Univ, Dept Chem, Sci & Res Branch, Tehran, Iran
来源：
TETRAHEDRON LETTERS | 2011年 / 52卷 / 49期
关键词：
delta-Sultams; Enaminones; N-Sulfonylation; Styrenesulfonyl chlorides; DIELS-ALDER REACTIONS; CYCLIC SULFONAMIDES; CYCLIZATION; AZIRIDINATION;
D O I：
10.1016/j.tetlet.2011.09.146
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis of novel delta-sultam scaffolds utilizing one-pot, three-component reactions of 1,3-dicarbonyl compounds, primary aliphatic amines and substituted styrenesulfonyl chlorides is reported. A variety of six-membered sultams are obtained in moderate to good yields presumably via N-sulfonylation-intramolecular Michael addition sequences. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码：6613 / 6615
页数：3
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