Molecular characterization of Italian Candida parapsilosis isolates reveals the cryptic presence of the newly described species Candida orthopsilosis in blood cultures from newborns

被引：17
作者：
Romeo, Orazio [1 ]
Delfino, Demetrio [2 ]
Costanzo, Barbara [1 ]
Cascio, Antonio [3 ]
Criseo, Giuseppe [1 ]
机构：
[1] Univ Messina, Dept Life Sci, Marcello Malpighi Sect Microbiol Genet & Mol Sci, I-98166 Messina, Italy
[2] Univ Messina, Sch Med, Dept Pathol & Expt Microbiol, I-98125 Messina, Italy
[3] Univ Messina, Dept Human Pathol, I-98125 Messina, Italy
来源：
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2012年 / 72卷 / 03期
关键词：
Candida parapsilosis; Candida orthopsilosis; Candida metapsilosis; Molecular epidemiology; SADH gene; ITS-sequencing; Newborns; ANTIFUNGAL SUSCEPTIBILITY; METAPSILOSIS; IDENTIFICATION; EPIDEMIOLOGY; SURVEILLANCE; VIRULENT;
D O I：
10.1016/j.diagmicrobio.2011.12.002
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
The authors report the molecular characterization of Candida parapsilosis isolates recovered from the blood and venous central catheter tips of patients admitted to different care units of the Polyclinic Hospital, University of Messina, Italy. Among 97 presumed C. parapsilosis isolates examined, 94 were identified as C. parapsilosis sensu stricto and the remaining 3 isolates were found to belong to the cryptic species Candida orthopsilosis which was recovered only from blood cultures of neonates (<30 days old) born prematurely. No C. metapsilosis was found in this study. This study emphasizes the role of C. parapsilosis as an important nosocomial pathogen, and it also describes, for the first time, the occurrence of C. orthopsilosis in newborns. (C) 2012 Elsevier Inc. All rights reserved.
引用
收藏
页码：234 / 238
页数：5
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