A primer on sex differences in the behavioral response to stress

被引:8
|
作者
Hodes, Georgia E. [1 ]
机构
[1] Virginia Polytech Inst & State Univ, Dept Neurosci, Blacksburg, VA 24061 USA
关键词
EARLY-LIFE STRESS; SOCIAL DEFEAT STRESS; CHRONIC MILD STRESS; PASSIVE-AVOIDANCE BEHAVIOR; TERM POTENTIATION LTP; FORCED SWIM TEST; ESTROUS-CYCLE; FEMALE RATS; MATERNAL SEPARATION; INESCAPABLE SHOCK;
D O I
10.1016/j.cobeha.2018.03.012
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
There is a growing interest, along with new technology, to perform translational research into the biology underlying many mental disorders and examining these effects in both sexes. Many studies use behavioral manipulations or endpoints to model these disorders in animals. However, some of these paradigms produce sex-skewed results that could influence and confound results. This review explores the behavioral literature on acute and chronic stress paradigms and their effects on behavior in males and females. We provide a guideline of which tests and behaviors are biased towards one sex or the other as tool to use in the design of stress-based experiments incorporating both sexes.
引用
收藏
页码:75 / 83
页数:9
相关论文
共 50 条
  • [21] Sex differences in synaptic plasticity in stress-responsive brain regions following chronic variable stress
    Carvalho-Netto, Eduardo F.
    Myers, Brent
    Jones, Kenneth
    Solomon, Matia B.
    Herman, James P.
    PHYSIOLOGY & BEHAVIOR, 2011, 104 (02) : 242 - 247
  • [22] Sex differences in (+)-amphetamine- and (+)-methamphetamine-induced behavioral response in male and female Sprague-Dawley rats
    Milesi-Halle, Alessandra
    McMillan, Donald E.
    Laurenzana, Elizabeth M.
    Byrnes-Blake, Kelly A.
    Owens, S. Michael
    PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2007, 86 (01) : 140 - 149
  • [23] Sex differences in neurogenesis and activation of new neurons in response to spatial learning and memory
    Chow, Carmen
    Epp, Jonathan R.
    Lieblich, Stephanie E.
    Barha, Cindy K.
    Galea, Liisa A. M.
    PSYCHONEUROENDOCRINOLOGY, 2013, 38 (08) : 1236 - 1250
  • [24] Sex differences in stress responses: Focus on ovarian hormones
    Ter Horst, Gert J.
    Wichmann, Romy
    Gerrits, Marjolein
    Westenbroek, Christel
    Lin, Yanhua
    PHYSIOLOGY & BEHAVIOR, 2009, 97 (02) : 239 - 249
  • [25] Mechanisms of Sex Differences in Fear and Posttraumatic Stress Disorder
    Ramikie, Teniel Sonya
    Ressler, Kerry J.
    BIOLOGICAL PSYCHIATRY, 2018, 83 (10) : 876 - 885
  • [26] Endocrinological basis of sex differences in cocaine-induced behavioral responses
    Quiñones-Jenab, V
    Perrotti, LI
    Fabian, SJ
    Chin, J
    Russo, SJ
    Jenab, S
    BIOLOGICAL BASIS OF COCAINE ADDICTION, 2001, 937 : 140 - 171
  • [27] Sex differences in behavioral and neurochemical effects of gonadectomy and aromatase inhibition in rats
    Kokras, N.
    Pastromas, N.
    Papasava, D.
    de Bournonville, C.
    Cornil, C. A.
    Dalla, C.
    PSYCHONEUROENDOCRINOLOGY, 2018, 87 : 93 - 107
  • [28] Sex differences in the drinking response to angiotensin II (AngII): Effect of body weight
    Santollo, Jessica
    Torregrossa, Ann-Marie
    Daniels, Derek
    HORMONES AND BEHAVIOR, 2017, 93 : 128 - 136
  • [29] Sex Differences in Behavioral Responding and Dopamine Release during Pavlovian Learning
    Lefner, Merridee J.
    Dejeux, Mariana I.
    Wanat, Matthew J.
    ENEURO, 2022, 9 (02)
  • [30] Sex differences in chronic stress effects on cognition in rodents
    Luine, Victoria
    Gomez, Juan
    Beck, Kevin
    Bowman, Rachel
    PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2017, 152 : 13 - 19