A primer on sex differences in the behavioral response to stress
被引:8
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作者:
Hodes, Georgia E.
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Virginia Polytech Inst & State Univ, Dept Neurosci, Blacksburg, VA 24061 USAVirginia Polytech Inst & State Univ, Dept Neurosci, Blacksburg, VA 24061 USA
Hodes, Georgia E.
[1
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机构:
[1] Virginia Polytech Inst & State Univ, Dept Neurosci, Blacksburg, VA 24061 USA
There is a growing interest, along with new technology, to perform translational research into the biology underlying many mental disorders and examining these effects in both sexes. Many studies use behavioral manipulations or endpoints to model these disorders in animals. However, some of these paradigms produce sex-skewed results that could influence and confound results. This review explores the behavioral literature on acute and chronic stress paradigms and their effects on behavior in males and females. We provide a guideline of which tests and behaviors are biased towards one sex or the other as tool to use in the design of stress-based experiments incorporating both sexes.
机构:
Univ Arkansas Med Sci, Dept Pharmacol & Toxicol, Coll Med, Little Rock, AR 72205 USAUniv Arkansas Med Sci, Dept Pharmacol & Toxicol, Coll Med, Little Rock, AR 72205 USA
Milesi-Halle, Alessandra
McMillan, Donald E.
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Univ Arkansas Med Sci, Dept Pharmacol & Toxicol, Coll Med, Little Rock, AR 72205 USAUniv Arkansas Med Sci, Dept Pharmacol & Toxicol, Coll Med, Little Rock, AR 72205 USA
McMillan, Donald E.
Laurenzana, Elizabeth M.
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Univ Arkansas Med Sci, Dept Pharmacol & Toxicol, Coll Med, Little Rock, AR 72205 USAUniv Arkansas Med Sci, Dept Pharmacol & Toxicol, Coll Med, Little Rock, AR 72205 USA
Laurenzana, Elizabeth M.
Byrnes-Blake, Kelly A.
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机构:
Univ Arkansas Med Sci, Dept Pharmacol & Toxicol, Coll Med, Little Rock, AR 72205 USAUniv Arkansas Med Sci, Dept Pharmacol & Toxicol, Coll Med, Little Rock, AR 72205 USA
Byrnes-Blake, Kelly A.
Owens, S. Michael
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Univ Arkansas Med Sci, Dept Pharmacol & Toxicol, Coll Med, Little Rock, AR 72205 USAUniv Arkansas Med Sci, Dept Pharmacol & Toxicol, Coll Med, Little Rock, AR 72205 USA
机构:
Univ British Columbia, Brain Res Ctr, Dept Psychol, Program Neurosci, Vancouver, BC V5Z 1M9, CanadaUniv British Columbia, Brain Res Ctr, Dept Psychol, Program Neurosci, Vancouver, BC V5Z 1M9, Canada
Chow, Carmen
Epp, Jonathan R.
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机构:
Univ British Columbia, Brain Res Ctr, Dept Psychol, Program Neurosci, Vancouver, BC V5Z 1M9, CanadaUniv British Columbia, Brain Res Ctr, Dept Psychol, Program Neurosci, Vancouver, BC V5Z 1M9, Canada
Epp, Jonathan R.
Lieblich, Stephanie E.
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机构:
Univ British Columbia, Brain Res Ctr, Dept Psychol, Program Neurosci, Vancouver, BC V5Z 1M9, CanadaUniv British Columbia, Brain Res Ctr, Dept Psychol, Program Neurosci, Vancouver, BC V5Z 1M9, Canada
Lieblich, Stephanie E.
Barha, Cindy K.
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Univ British Columbia, Brain Res Ctr, Dept Psychol, Program Neurosci, Vancouver, BC V5Z 1M9, CanadaUniv British Columbia, Brain Res Ctr, Dept Psychol, Program Neurosci, Vancouver, BC V5Z 1M9, Canada
Barha, Cindy K.
Galea, Liisa A. M.
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机构:
Univ British Columbia, Brain Res Ctr, Dept Psychol, Program Neurosci, Vancouver, BC V5Z 1M9, CanadaUniv British Columbia, Brain Res Ctr, Dept Psychol, Program Neurosci, Vancouver, BC V5Z 1M9, Canada
机构:Univ Texas San Antonio, Neurosci Inst, San Antonio, TX 78249 USA
Lefner, Merridee J.
Dejeux, Mariana I.
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机构:Univ Texas San Antonio, Neurosci Inst, San Antonio, TX 78249 USA
Dejeux, Mariana I.
Wanat, Matthew J.
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机构:
Univ Texas San Antonio, Neurosci Inst, San Antonio, TX 78249 USA
Univ Texas San Antonio, Dept Neurosci Dev & Regenerat Biol, San Antonio, TX 78249 USAUniv Texas San Antonio, Neurosci Inst, San Antonio, TX 78249 USA
机构:
CUNY Hunter Coll, Dept Psychol, 695 Pk Ave, New York, NY 10065 USACUNY Hunter Coll, Dept Psychol, 695 Pk Ave, New York, NY 10065 USA
Luine, Victoria
Gomez, Juan
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机构:
NIDA, Biobehav Imaging & Mol Neuropsychopharmacol, Baltimore, MD 21224 USACUNY Hunter Coll, Dept Psychol, 695 Pk Ave, New York, NY 10065 USA
Gomez, Juan
Beck, Kevin
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机构:
VA NJ Hlth Care Syst, Neurobehav Res Lab, E Orange, NJ 07018 USA
Rutgers New Jrersey Med Sch, Dept Pharmacol Physiol & Neurosci, Newark, NJ 07103 USACUNY Hunter Coll, Dept Psychol, 695 Pk Ave, New York, NY 10065 USA
Beck, Kevin
Bowman, Rachel
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机构:
Sacred Heart Univ, Dept Psychol, Fairfield, CT 06825 USACUNY Hunter Coll, Dept Psychol, 695 Pk Ave, New York, NY 10065 USA