Colorimetric Enantiorecognition of Oligopeptide and Logic Gate Construction Based on DNA Aptamer-Ligand-Gold Nanoparticle Interactions

被引:31
作者
Ren, Jiangtao [1 ,2 ]
Wang, Jiahai [1 ,3 ]
Wang, Jin [1 ]
Wang, Erkang [1 ]
机构
[1] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroanalyt Chem, Changchun 130022, Jilin, Peoples R China
[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
[3] SUNY Stony Brook, Dept Chem & Phys, Stony Brook, NY 11794 USA
基金
美国国家科学基金会; 中国国家自然科学基金;
关键词
aptamers; enantioselectivity; gold nanoparticles; logic gates; oligopeptides; CHIRAL RECOGNITION; HIV-1; ENTRY; BINDING; NUCLEATION; SEPARATION; PEPTIDES; SELECTOR; DESIGN; SIZE;
D O I
10.1002/chem.201202430
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
At the gate: Colorimetric enantiorecognition of one oligopeptide was realized by virtue of a D-enantiomer specific DNA aptamer as chiral selector and unmodified gold nanoparticles as indicator. Oligopeptide enantiomers as inputs were introduced into colorimetric logic gates, which have the potential for enantiorecognition of oligopeptides (see figure). This system may lead to a better understanding of chiral recognition for information processing in natural systems.
引用
收藏
页码:478 / 482
页数:5
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