A Low-Power Integrated Bioamplifier With Active Low-Frequency Suppression

被引：109

作者：

Gosselin, Benoit ^{[1
]}

Sawan, Mohamad ^{[1
]}

Chapman, C. Andrew ^{[2
]}

机构：

[1] Ecole Polytech, Dept Elect Engn, Polystim Neurotechnol Lab, Montreal, PQ H3C 3A7, Canada

[2] Concordia Univ, Ctr Studies Behav Neurobiol, Dept Psychol, Montreal, PQ H4B 1R6, Canada

来源：

IEEE TRANSACTIONS ON BIOMEDICAL CIRCUITS AND SYSTEMS | 2007年 / 1卷 / 03期

基金：

加拿大自然科学与工程研究理事会;

关键词：

Active low-frequency suppression; biopotential recording; dense integrated neural interfaces; integrated bioamplifier; micropower analog circuit design;

D O I：

10.1109/TBCAS.2007.914490

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

We present in this paper a low-power bioamplifier suitable for massive integration in dense multichannel recording devices. This bioamplifier achieves reduced-size compared to previous designs by means of active low-frequency suppression. An active integrator located in the feedback path of a low-noise amplifier is employed for placing a highpass cutoff frequency within the transfer function. A very long integrating time constant is achieved using a small integrated capacitor and a MOS-bipolar equivalent resistor. This configuration rejects unwanted low-frequency contents without the need for input RC networks or large feedback capacitors. Therefore, the bioamplifier high-input impedance and small size are preserved. The bioamplifier, implemented in a 0.18-mu m CMOS process, has been designed for neural recording of action potentials, and optimised through a transconductance-efficiency design methodology for micropower operation. Measured performance and results obtained from in vivo recordings are presented. The integrated bioamplifier provides a midband gain of 50 dB, and achieves an input-referred noise of 5.6 mu Vrms. It occupies less than 0.050 mm(2) of chip area and dissipates 8.6 mu W.

引用

页码：184 / 192

页数：9