Reversals and transpositions over finite alphabets

被引:34
|
作者
Radcliffe, AJ [1 ]
Scott, AD
Wilmer, EL
机构
[1] Univ Nebraska, Dept Math, Lincoln, NE 68588 USA
[2] UCL, Dept Math, London WC1E 6BT, England
[3] Oberlin Coll, Dept Math, Oberlin, OH 44074 USA
关键词
strings; sorting; genome comparison; reversals; transpositions; NP-complete problems; MAX-SNP hardness; approximation algorithms;
D O I
10.1137/S0895480103433550
中图分类号
O29 [应用数学];
学科分类号
070104 ;
摘要
Extending results of Christie and Irving, we examine the action of reversals and transpositions on finite strings over an alphabet of size k. We show that determining reversal, transposition, or signed reversal distance between two strings over a finite alphabet is NP-hard, while for "dense" instances we give a polynomial-time approximation scheme. We also give a number of extremal results, as well as investigating the distance between random strings and the problem of sorting a string over a finite alphabet.
引用
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页码:224 / 244
页数:21
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