Serotype Distribution of Streptococcus pneumoniae causing Invasive Pneumococcal Disease at Bambino Gesu Children's Hospital in Rome: Is It Time for a New Vaccine?

被引：2

作者：

Nicolosi, Luciana ^{[1
]}

Bozzola, Elena ^{[1
]}

Krzysztofiak, Andrzej ^{[1
]}

Pantosti, Annausa ^{[2
]}

Lancella, Laura ^{[1
]}

Bernaschi, Paola ^{[3
]}

Marchili, Maria Rosaria ^{[1
]}

Villani, Alberto ^{[1
]}

机构：

[1] Bambino Gesu Pediat Hosp, UOC Pediat & Infect Dis, Rome, Italy

[2] Natl Inst Hlth, Dept Infect Parasit & Immune Mediated Dis, Rome, Italy

[3] Bambino Gesu Pediat Hosp, UOS Microbiol, Rome, Italy

来源：

JOURNAL OF PEDIATRIC INFECTIOUS DISEASES | 2019年 / 14卷 / 01期

关键词：

vaccine; Streptococcus pneumoniae; invasive disease; children; CONJUGATE VACCINE;

D O I：

10.1055/s-0037-1615784

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Diseases caused by Streptococcus pneumoniae are mostly preventable infections by current immunization programs. The objective of this study was to evaluate the impact of the introduction of the heptavalent and the 13-valent pneumococcal conjugate vaccines (PCV7 and PCV13) on the burden of pneumococcal disease and on the serotype distribution of S. pneumoniae causing invasive pneumococcal diseases (IPDs) in the pediatric age over a 5-year study (from January 2008 till December 2012). We observed a decrease in IPD rate in children after PCV13 introduction despite increases in nonvaccine serotype (NVS) rates in 2011. Nevertheless, from 2012, an increase in IPD rates due to non-PCV13 serotypes was observed.

引用

页码：13 / 15

页数：3

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