Gold mining for PDT: Great expectations from tiny nanoparticles

被引：35

作者：

Gamaleia, Nikolai F. ^{[1
]}

Shton, Irina O. ^{[1
]}

机构：

[1] Natl Acad Sci Ukraine, RE Kavetsky Inst Expt Pathol Oncol & Radiobiol, Lab Quantum Nanobiol, UA-03022 Kiev, Ukraine

来源：

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY | 2015年 / 12卷 / 02期

关键词：

Nanoparticles; Nanogold; Photodynannic therapy; Photosensitizers; PHOTODYNAMIC THERAPY; SUBCELLULAR-LOCALIZATION; CELLULAR UPTAKE; ALUMINUM PHTHALOCYANINES; POTENTIAL APPLICATIONS; DRUG-DELIVERY; CHLORIN E6; PHOTOSENSITIZERS; FLUORESCENCE; SIZE;

D O I：

10.1016/j.pdpdt.2015.03.002

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Among many and various products, born by the modern nanotechnology, gold nanoparticles roused a special interest of biomedical researchers. Unique features of the nanoparticles allow to use them not only as effective transporters for therapeutic agents but also as basic components of nanocomposite preparations intended for targeted photodynamic and photothermal therapy of tumours. In the review, physical, chemical and biological properties of gold nanoparticles which can promote PDT efficiency of a designed nanocomposite, are briefly characterized, and promising trends in creation of gold-containing composite photosensitizers are analysed. (c) 2015 Elsevier B.V. All rights reserved.

引用

页码：221 / 231

页数：11

共 91 条

[1] Targeted epidermal growth factor receptor nanoparticle bioconjugates for breast cancer therapy [J].

Acharya, Sarbari ;

Dilnawaz, Fahima ;

Sahoo, Sanjeeb K. .

BIOMATERIALS, 2009, 30 (29) :5737-5750

[2]

Alexis Frank, 2010, Handb Exp Pharmacol, P55, DOI 10.1007/978-3-642-00477-3_2

[3] Toxicity and cellular uptake of gold nanoparticles: what we have learned so far? [J].

Alkilany, Alaaldin M. ;

Murphy, Catherine J. .

JOURNAL OF NANOPARTICLE RESEARCH, 2010, 12 (07) :2313-2333

[4] Mechanism of anti-angiogenic property of gold nanoparticles: role of nanoparticle size and surface charge [J].

Arvizo, Rochelle R. ;

Rana, Subinoy ;

Miranda, Oscar R. ;

Bhattacharya, Resham ;

Rotello, Vincent M. ;

Mukherjee, Priyabrata .

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2011, 7 (05) :580-587

[5] Lysosomes and microtubules as targets for photochemotherapy of cancer [J].

Berg, K ;

Moan, J .

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1997, 65 (03) :403-409

[6] CELLULAR UPTAKE AND RELATIVE EFFICIENCY IN CELL INACTIVATION BY PHOTOACTIVATED SULFONATED MESO-TETRAPHENYLPORPHINES [J].

BERG, K ;

BOMMER, JC ;

WINKELMAN, JW ;

MOAN, J .

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1990, 52 (04) :775-781

[7] Gold nanoparticles in nanomedicine: preparations, imaging, diagnostics, therapies and toxicity [J].

Boisselier, Elodie ;

Astruc, Didier .

CHEMICAL SOCIETY REVIEWS, 2009, 38 (06) :1759-1782

[8] Probing BSA binding to citrate-coated gold nanoparticles and surfaces [J].

Brewer, SH ;

Glomm, WR ;

Johnson, MC ;

Knag, MK ;

Franzen, S .

LANGMUIR, 2005, 21 (20) :9303-9307

[9] SYNTHESIS OF THIOL-DERIVATIZED GOLD NANOPARTICLES IN A 2-PHASE LIQUID-LIQUID SYSTEM [J].

BRUST, M ;

WALKER, M ;

BETHELL, D ;

SCHIFFRIN, DJ ;

WHYMAN, R .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1994, (07) :801-802

[10] Active targeting schemes for nanoparticle systems in cancer therapeutics [J].

Byrne, James D. ;

Betancourt, Tania ;

Brannon-Peppas, Lisa .

ADVANCED DRUG DELIVERY REVIEWS, 2008, 60 (15) :1615-1626

← 1 2 3 4 5 6 7 8 9 10 →