Antimicrobial Actions of Reactive Oxygen Species

被引：269
作者：
Fang, Ferric C. [1 ,2 ]
机构：
[1] Univ Washington, Sch Med, Dept Lab Med, Seattle, WA 98195 USA
[2] Univ Washington, Sch Med, Dept Microbiol, Seattle, WA 98195 USA
来源：
MBIO | 2011年 / 2卷 / 05期
关键词：
CHRONIC GRANULOMATOUS-DISEASE; ENTERICA SEROVAR TYPHIMURIUM; NADPH PHAGOCYTE OXIDASE; SALMONELLA PATHOGENICITY ISLAND-2; OXIDATIVE STRESS RESISTANCE; GREEN FLUORESCENT PROTEIN; ZN-SUPEROXIDE DISMUTASES; III SECRETION SYSTEM; BASE EXCISION-REPAIR; NITRIC-OXIDE;
D O I：
10.1128/mBio.00141-11
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Reactive oxygen species (ROS) are produced by host phagocytes and exert antimicrobial actions against a broad range of pathogens. The observable antimicrobial actions of ROS are highly dependent on experimental conditions. This perspective reviews recent controversies regarding ROS in Salmonella-phagocyte interactions and attempts to reconcile conflicting observations from different laboratories.
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页数：6
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