Palladium-catalyzed synthesis of nitriles from N-phthaloyl hydrazones

被引：8
作者：
Ano, Yusuke [1 ,2 ]
Higashino, Masaya [1 ]
Yamada, Yuki [1 ]
Chatani, Naoto [1 ]
机构：
[1] Osaka Univ, Dept Appl Chem, Fac Engn, Suita, Osaka 5650871, Japan
[2] Osaka Univ, Grad Sch Engn, Ctr Atom & Mol Technol, Suita, Osaka 5650871, Japan
来源：
CHEMICAL COMMUNICATIONS | 2022年 / 58卷 / 23期
关键词：
C-H ACTIVATION; BOND-CLEAVAGE; ORGANIC-SYNTHESIS; COMPLEXES NHC; CONVERSION; N; N-DIMETHYLHYDRAZONES; OXIDATION; ALDEHYDES; N-DIALKYLHYDRAZONES; TRANSFORMATION;
D O I：
10.1039/d2cc00342b
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The Pd-catalyzed transformation of N-phthaloyl hydrazones into nitriles involving the cleavage of an N-N bond is reported. The use of N-heterocyclic carbene as a ligand is essential for the success of the reaction. N-Phthaloyl hydrazones prepared from aromatic aldehydes or cyclobutanones are applicable to this transformation, which gives aryl or alkenyl nitriles, respectively.
引用
收藏
页码：3799 / 3802
页数：4
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