Alignment and phylogenetic analysis of type II DNA topoisomerases

被引：20

作者：

Madhusudan, K ^{[1
]}

Nagaraja, V ^{[1
]}

机构：

[1] INDIAN INST SCI,CTR GENET ENGN,BANGALORE 560012,KARNATAKA,INDIA

来源：

JOURNAL OF BIOSCIENCES | 1996年 / 21卷 / 05期

关键词：

type II DNA topoisomerases; DNA gyrase; multiple alignment; phylogenetic trees;

D O I：

10.1007/BF02703140

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

DNA topoisomerases have been evolved to solve the topological problems of DNA during replication, transcription, recombination and segregation. Discovery of several new enzymes and their characterization has necessitated this compilation. This analysis shows the distinct evolutionary relatedness of type II DNA topoisomerases. A striking feature is the absence of a contiguous stretch of about 160 amino acids in one of the subunits of prokaryotic type II enzymes, which might have important implications to their structure and function.

引用

页码：613 / 629

页数：17

共 49 条

[1] CHARACTERIZATION OF CDNA-ENCODING THE MOUSE DNA TOPOISOMERASE-II THAT CAN COMPLEMENT THE BUDDING YEAST TOP2 MUTATION [J].

ADACHI, N ;

MIYAIKE, M ;

IKEDA, H ;

KIKUCHI, A .

NUCLEIC ACIDS RESEARCH, 1992, 20 (20) :5297-5303

[2] DNA-SEQUENCE OF THE ESCHERICHIA-COLI GYRB GENE - APPLICATION OF A NEW SEQUENCING STRATEGY [J].

ADACHI, T ;

MIZUUCHI, M ;

ROBINSON, EA ;

APPELLA, E ;

ODEA, MH ;

GELLERT, M ;

MIZUUCHI, K .

NUCLEIC ACIDS RESEARCH, 1987, 15 (02) :771-784

[3] AFRICAN SWINE FEVER VIRUS ENCODES A GENE WITH EXTENSIVE HOMOLOGY TO TYPE-II DNA TOPOISOMERASES [J].

BAYLIS, SA ;

DIXON, LK ;

VYDELINGUM, S ;

SMITH, GL .

JOURNAL OF MOLECULAR BIOLOGY, 1992, 228 (03) :1003-1010

[4] Recent developments in DNA topoisomerase II structure and mechanism [J].

Berger, JM ;

Wang, JC .

CURRENT OPINION IN STRUCTURAL BIOLOGY, 1996, 6 (01) :84-90

[5] Structure and mechanism of DNA topoisomerase II [J].

Berger, JM ;

Gamblin, SJ ;

Harrison, SC ;

Wang, JC .

NATURE, 1996, 379 (6562) :225-232

[6]

CALCUTT MJ, 1994, GENE, V146, P117

[7]

CARON PR, 1993, MOLECULAR BIOLOGY OF DNA TOPOISOMERASES AND ITS APPLICATION CHEMOTHERAPY, P1

[8] MYCOPLASMA-PNEUMONIAE DNA GYRASE GENES [J].

COLMAN, SD ;

HU, PC ;

BOTT, KF .

MOLECULAR MICROBIOLOGY, 1990, 4 (07) :1129-1134

[9] MULTIPLE SEQUENCE ALIGNMENT WITH HIERARCHICAL-CLUSTERING [J].

CORPET, F .

NUCLEIC ACIDS RESEARCH, 1988, 16 (22) :10881-10890

[10] CLONING AND SEQUENCE-ANALYSIS OF GYRA GENE OF KLEBSIELLA-PNEUMONIAE [J].

DIMRI, GP ;

DAS, HK .

NUCLEIC ACIDS RESEARCH, 1990, 18 (01) :151-156

← 1 2 3 4 5 →