Clean synthesis in water. Part 2: Uncatalysed condensation reaction of Meldrum's acid and aldehydes

被引：167

作者：

Bigi, F ^{[1
]}

Carloni, S ^{[1
]}

Ferrari, L ^{[1
]}

Maggi, R ^{[1
]}

Mazzacani, A ^{[1
]}

Sartori, G ^{[1
]}

机构：

[1] Univ Parma, Dipartimemto Chim Organ & Ind, I-43100 Parma, Italy

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 31期

关键词：

Meldrum's acid; water; uncatalysed reaction; Knoevenagel condensation; arylidene Meldrum's acid; environmentally benign synthesis;

D O I：

10.1016/S0040-4039(01)00978-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The environment-friendly condensation of Meldrum's acid and aromatic, heteroaromatic and hindered aliphatic aldehydes is performed carrying out the reaction in water at 75 degreesC for 2 h, avoiding the addition of any catalyst. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：5203 / 5205

页数：3

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