Characterization of Early-Onset Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Immunocompromised Patients Who Received Tixagevimab-Cilgavimab Prophylaxis

被引：16

作者：

Ordaya, Eloy E. ^{[1
]}

Beam, Elena ^{[1
]}

Yao, Joseph D. ^{[2
]}

Razonable, Raymund R. ^{[1
]}

Vergidis, Paschalis ^{[1
]}

机构：

[1] Mayo Clin, Div Infect Dis, Dept Med, 200 First St SW, Rochester, MN 55905 USA

[2] Mayo Clin, Div Clin Microbiol, Dept Lab Med & Pathol, Rochester, MN 55905 USA

来源：

OPEN FORUM INFECTIOUS DISEASES | 2022年 / 9卷 / 07期

关键词：

COVID-19; immunocompromised hosts; monoclonal antibodies; transplant infectious diseases;

D O I：

10.1093/ofid/ofac283

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Tixagevimab-cilgavimab is authorized for preexposure prophylaxis against coronavirus disease 2019 (COVID-19) in immunocompromised hosts. Herein, we report the clinical characteristics of 8 patients who developed COVID-19 soon after receiving tixagevimab-cilgavimab. This study emphasizes the need to maintain additional measures to prevent COVID-19 during periods of high severe acute respiratory syndrome coronavirus 2 transmission.

引用

页数：5

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