ER proteostasis disturbances in Parkinson's disease: novel insights

被引：22

作者：

Mercado, Gabriela ^{[1
,2
]}

Castillo, Valentina ^{[1
,2
]}

Vidal, Rene ^{[1
,3
]}

Hetz, Claudio ^{[1
,2
,4
]}

机构：

[1] Univ Chile, Fac Med, Biomed Neurosci Inst, Santiago 7, Chile

[2] Univ Chile, Inst Biomed Sci, Program Cellular & Mol Biol, Santiago 7, Chile

[3] CENPAR, Neurounion Biomed Fdn, Santiago, Chile

[4] Harvard Univ, Sch Publ Hlth, Dept Immunol & Infect Dis, Boston, MA 02115 USA

来源：

FRONTIERS IN AGING NEUROSCIENCE | 2015年 / 7卷

关键词：

UPR signaling pathways; Parkinson disease; gene therapy; preclinical models; dopaminergic neurons; ER stress; UNFOLDED PROTEIN RESPONSE; TRANSCRIPTION FACTOR XBP1; RAT MODEL; IN-VIVO; STRESS; AUTOPHAGY; NEURONS; NEUROTOXICITY; ACTIVATION; DEATH;

D O I：

10.3389/fnagi.2015.00039

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

[No abstract available]

引用

页数：5

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