Histone H3K4 methylation keeps centromeres open for business

被引：11

作者：

Stimpson, Keitlin M. ^{[1
,2
]}

Sullivan, Beth A. ^{[1
,2
]}

机构：

[1] Duke Univ, Med Ctr, Dept Mol Genet & Microbiol, Durham, NC 27706 USA

[2] Duke Univ, Duke Inst Genome Sci & Policy, Durham, NC USA

来源：

EMBO JOURNAL | 2011年 / 30卷 / 02期

关键词：

CHROMATIN; KINETOCHORE; RNAS;

D O I：

10.1038/emboj.2010.339

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Eukaryotic centromeres are composed of a combination of nucleosomes containing the histone H3 variant CENP-A and canonical H3 di-methylated at lysine 4 (H3K4me2). Many questions exist over the functional importance of H3K4me2 nucleosomes within the centromere region. In this issue of The EMBO Journal, Bergmann et al (2011) reveal a role for H3K4me2 and transcription in CENP-A maintenance. They also extend the profile of centromeric histone modifications to include H3K36 methylation, typically found at transcribed regions of the genome.

引用

页码：233 / 234

页数：2

共 50 条

[31] Crosstalk between NSL Histone Acetyltransferase and MLL/SET Complexes: NSL Complex Functions in Promoting Histone H3K4 Di-Methylation Activity by MLL/SET Complexes
Zhao, Xiaoming
Su, Jiaming
Wang, Fei
Liu, Da
Ding, Jian
Yang, Yang
Conaway, Joan W.
Conaway, Ronald C.
Cao, Lingling
Wu, Donglu
Wu, Min
Cai, Yong
Jin, Jingji
PLOS GENETICS, 2013, 9 (11):
[32] Histone H2BK123 monoubiquitination is the critical determinant for H3K4 and H3K79 trimethylation by COMPASS and Dot1
Nakanishi, Shima
Lee, Jung Shin
Gardner, Kathryn E.
Gardner, Jennifer M.
Takahashi, Yoh-hei
Chandrasekharan, Mahesh B.
Sun, Zu-Wen
Osley, Mary Ann
Strahl, Brian D.
Jaspersen, Sue L.
Shilatifard, Ali
JOURNAL OF CELL BIOLOGY, 2009, 186 (03) : 371 - 377
[33] Drosophila Hcf regulates the Hippo signaling pathway via association with the histone H3K4 methyltransferase Trr
Nan, Zi
Yang, Weiwei
Lyu, Jialan
Wang, Fang
Deng, Qiannan
Xi, Yongmei
Yang, Xiaohang
Ge, Wanzhong
BIOCHEMICAL JOURNAL, 2019, 476 : 759 - 768
[34] Nucleolar protein Spindlin1 recognizes H3K4 methylation and stimulates the expression of rRNA genes
Wang, Weixiang
Chen, Zhi
Mao, Zhuo
Zhang, Huihui
Ding, Xiaojun
Chen, She
Zhang, Xiaodong
Xu, Ruiming
Zhu, Bing
EMBO REPORTS, 2011, 12 (11) : 1160 - 1166
[35] The many faces of histone H3K79 methylation
Farooq, Zeenat
Banday, Shahid
Pandita, Tej K.
Altaf, Mohammad
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH, 2016, 768 : 46 - 52
[36] An acetylation-mediated chromatin switch governs H3K4 methylation read-write capability
Jain, Kanishk
Marunde, Matthew R.
Burg, Jonathan M.
Gloor, Susan L.
Joseph, Faith M.
Poncha, Karl F.
Gillespie, Zachary B.
Rodriguez, Keli L.
Popova, Irina K.
Hall, Nathan W.
Vaidya, Anup
Howard, Sarah A.
Taylor, Hailey F.
Mukhsinova, Laylo
Onuoha, Ugochi C.
Patteson, Emily F.
Cooke, Spencer W.
Taylor, Bethany C.
Weinzapfel, Ellen N.
Cheek, Marcus A.
Meiners, Matthew J.
Fox, Geoffrey C.
Namitz, Kevin E. W.
Cowles, Martis W.
Krajewski, Krzysztof
Sun, Zu-Wen
Cosgrove, Michael S.
Young, Nicolas L.
Keogh, Michael-Christopher
Strahl, Brian D.
ELIFE, 2023, 12
[37] Histone H3 lysine 4 methylation revisited
Kusch, Thomas
TRANSCRIPTION-AUSTIN, 2012, 3 (06): : 310 - 314
[38] H3K4 methylation at active genes mitigates transcription-replication conflicts during replication stress
Chong, Shin Yen
Cutler, Sam
Lin, Jing-Jer
Tsai, Cheng-Hung
Tsai, Huai-Kuang
Biggins, Sue
Tsukiyama, Toshio
Lo, Yi-Chen
Kao, Cheng-Fu
NATURE COMMUNICATIONS, 2020, 11 (01)
[39] Histone H3 K36 methylation is mediated by a trans-histone methylation pathway involving an interaction between Set2 and histone H4
Du, Hai-Ning
Fingerman, Ian M.
Briggs, Scott D.
GENES & DEVELOPMENT, 2008, 22 (20) : 2786 - 2798
[40] CXXC finger protein 1 restricts the Setd1A histone H3K4 methyltransferase complex to euchromatin
Tate, Courtney M.
Lee, Jeong-Heon
Skalnik, David G.
FEBS JOURNAL, 2010, 277 (01) : 210 - 223

← 1 2 3 4 5 →