Nutraceutical Potential of Leaf Hydro-Ethanolic Extract of the Edible Halophyte Crithmum maritimum L.

被引:31
作者
Souid, Aymen [1 ,2 ]
Della Croce, Clara Maria [1 ]
Frassinetti, Stefania [1 ]
Gabriele, Morena [1 ]
Pozzo, Luisa [1 ]
Ciardi, Marco [1 ]
Abdelly, Chedly [2 ]
Ben Hamed, Karim [2 ]
Magne, Christian [3 ]
Longo, Vincenzo [1 ]
机构
[1] CNR, Inst Biol & Agr Biotechnol IBBA, Res Area Pisa, Via Moruzzi 1, I-56124 Pisa, Italy
[2] Ctr Biotechnol Borj Cedria, Lab Plantes Extremophiles, BP 901, Hammam Lif 2050, Tunisia
[3] Univ Brest, EA7462 Geoarchitecture Terr Urbanisat Biodiversit, 6 Ave Victor Le Gorgeu,CS 93837, F-29238 Brest 3, France
来源
MOLECULES | 2021年 / 26卷 / 17期
关键词
Crithmum maritimum L; antioxidant capacity; phytochemicals; antibacterial activity; antibiofilm activity; antimutagenic effect; functional food; ANTIOXIDANT ACTIVITY; ANTIMICROBIAL ACTIVITIES; ESSENTIAL OILS; ANTIBACTERIAL ACTIVITY; PHENOLIC COMPOSITION; BIOFILM FORMATION; CHLOROGENIC ACID; POLYPHENOLS; CAPACITY; PLANTS;
D O I
10.3390/molecules26175380
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Aromatic halophytes represent an exceptional source of natural bioactive compounds for the food industry. Crithmum maritimum L., also known as sea fennel, is a halophyte plant colonizing cliffs and coastal dunes along Mediterranean and Atlantic coasts. It is well known to produce essential oils and polyphenols endowed with antioxidant and biological effects. The present work reports the phytochemical profile, as well as antioxidant, antimicrobial and antimutagenic properties of C. maritimum leaf hydro-alcoholic extract. From LC-ESI-MS analysis, eighteen phenolic compounds were depicted in sea fennel extract and the amount of total phenolic content exceeds 3% DW. Accordingly, C. maritimum extract showed strong antioxidant activities, as evidenced by in vitro (DPPH, ORAC, FRAP) and ex vivo (CAA-RBC and hemolysis) assays. An important antimicrobial activity against pathogenic strains was found as well as a strong capacity to inhibit Staphylococcus aureus (ATCC 35556) biofilm formation. Sea fennel extracts showed a significant decrease of mutagenesis induced by hydrogen peroxide (H2O2) and menadione (ME) in Saccharomyces cerevisiae D7 strain. In conclusion, our results show that C. maritimum is an exceptional source of bioactive components and exert beneficial effects against oxidative or mutagenic mechanisms, and pathogenic bacteria, making it a potential functional food.
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页数:15
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