Copper-Catalyzed Aerobic Oxidation of Azinylmethanes for Access to Trifluoromethylazinylols

被引：21
作者：
Zheng, Gang [1 ]
Liu, Hao [1 ]
Wang, Mang [1 ]
机构：
[1] Northeast Normal Univ, Dept Chem, Changchun 130024, Jilin, Peoples R China
来源：
CHINESE JOURNAL OF CHEMISTRY | 2016年 / 34卷 / 05期
基金：
中国国家自然科学基金;
关键词：
aerobic oxidation; azinylmethanes; copper catalysis; synthetic methods; trifluoromethylation; SELECTIVE OXIDATION; EFFICIENT SYNTHESIS; DIRECT AMIDATION; FUNCTIONALIZATION;
D O I：
10.1002/cjoc.201500918
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A copper-catalyzed oxygenation of methylazaarenes was found to occur in the absence of both ligand and additive, and has been successfully employed for the synthesis of trifluoromethylazinylketols. This synthetic strategy incorporates aerobic oxidation and a trifluoromethylation in one-pot and provides a novel method for the trifluoromethylation of aliphatic C-H bond.
引用
收藏
页码：519 / 523
页数：5
相关论文
共 50 条
  • [31] Copper-Catalyzed Aerobic Oxidative Regioselective Thiocyanation of Aromatics and Heteroaromatics
    Jiang, Huanfeng
    Yu, Wentao
    Tang, Xiaodong
    Li, Jianxiao
    Wu, Wanqing
    JOURNAL OF ORGANIC CHEMISTRY, 2017, 82 (18) : 9312 - 9320
  • [32] Copper-Catalyzed Aerobic C(sp3)-H Oxidation of β-(Alkoxy)imino Carbonyl Compounds
    Ueda, Masafumi
    Ichimonji, Ayano
    Nakayama, Miku
    Ito, Sachiko
    Takeda, Norihiko
    Yasui, Motohiro
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2023, 71 (02) : 83 - 92
  • [33] Copper-Catalyzed Oxidation of Alkanes under Mild Conditions
    Garcia-Bosch, Isaac
    SYNLETT, 2017, 28 (11) : 1237 - 1243
  • [34] Copper-catalyzed enantioselective allylic oxidation of acyclic olefins
    Zhang, Bo
    Zhu, Shou-Fei
    Zhou, Qi-Lin
    TETRAHEDRON LETTERS, 2013, 54 (21) : 2665 - 2668
  • [35] An Efficient Strategy for Quinazolinone and Benzimidazole Synthesis Using Microwave-Assisted Copper-Catalyzed Aerobic Oxidation of Amines
    Bera, Shyamal Kanti
    Irfan, Muhammad
    Porcheddu, Andrea
    CHEMCATCHEM, 2025, 17 (06)
  • [36] Copper-catalyzed aerobic alcohol oxidation under air in neat water by using a water-soluble ligand
    Zhang, Guofu
    Han, Xingwang
    Luan, Yuxin
    Wang, Yong
    Wen, Xin
    Xu, Li
    Ding, Chengrong
    Gao, Jianrong
    RSC ADVANCES, 2013, 3 (42): : 19255 - 19258
  • [37] Copper-catalyzed aerobic aliphatic C-H oxygenation with hydroperoxides
    Too, Pei Chui
    Tnay, Ya Lin
    Chiba, Shunsuke
    BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 2013, 9 : 1217 - 1225
  • [38] Copper-Catalyzed Aerobic Decarboxylation/Ketooxygenation of Electron-Deficient Alkenes
    Lu, Qingquan
    Peng, Pan
    Luo, Yi
    Zhao, Ying
    Zhou, Minxian
    Lei, Aiwen
    CHEMISTRY-A EUROPEAN JOURNAL, 2015, 21 (51) : 18580 - 18583
  • [39] Copper-catalyzed aerobic oxidative dicarbonylation of indoles utilizing α-carbonyl aldehydes
    Yang, Jin-Ming
    Cai, Zhong-Jian
    Wang, Qing-Dong
    Fang, Dong
    Ji, Shun-Jun
    TETRAHEDRON, 2015, 71 (38) : 7010 - 7015
  • [40] Enantioselective, Aerobic Copper-Catalyzed Intramolecular Carboamination and Carboetherification of Unactivated Alkenes
    Wdowik, Tomasz
    Galster, Samuel L.
    Carmo, Raul L. L.
    Chemler, Sherry R.
    ACS CATALYSIS, 2020, 10 (15): : 8535 - 8541
12345