Genetic expression and clustering analysis related to DNA micro-arrays using optical sensor manufactured using silicon material

被引:0
作者
Padukone, G. Sowmya [1 ]
Umadevi, H. [2 ]
机构
[1] Visveswaraya Technol Univ, Oxford Coll Engn, Fac Elect & Commun Engn, Dept Elect & Commun Engn, Bangalore 560068, Karnataka, India
[2] Visveswaraya Technol Univ, Dr Ambedkar Inst Technol, Dept Elect & Commun Engn, Fac Elect & Commun Engn, Bangalore 560056, Karnataka, India
关键词
DNA; Intensity; Micro-array; Control diseases; Optical sensor;
D O I
10.1016/j.matpr.2021.12.345
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Every human being is different from each other. Every Organism has thousands of cell in their body. Genes encrypts Cells. The function of the cell is determined by Genes. Many diseases may occur due to Cell Mal function. The Cells in our body is different & based on Evolution of Cells the genetic Expression could be decided. The intensity of Proteins in our body decides the relative Genetic Expression in a Human body. The binding level of Proteins determines the Genetic Expression level. DNA levels decides the amount of Protein in our body. Measuring the Genetic Expression is a technique for determination of Characteristics of Living Organism. The Information encrypted within Genes produces Proteins. The procedure for making the Genes ON & OFF is said to be as Gene Regulation. Here DNA Micro-Array Analysis techniques have been used to measure Genetic Expression. The Relative Expression level of the Micro-Array Spots will be determined by Using Optical Sensor using MATLAB which a mathematical & Simulation Tool. Cancer is a Chromosomal disease. By Studying genetic expression, Cancer & other type of Diseases could be identified. Different types of Genes are identified & their relative Peak values & Intensity Values are determined. This Technique could be used to Control Cancer, Diabetes & other types of Diseases. The material used is made of Microscpic Glass Slide made up of Silicon (Si) material. Copyright (c) 2022 Elsevier Ltd. All rights reserved. Selection and peer-review under responsibility of the scientific committee of the International Conference on Design, Manufacturing and Materials Engineering.
引用
收藏
页码:1770 / 1779
页数:10
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