Myocardial injury after noncardiac surgery: facts, fallacies and how to approach clinically

被引：2

作者：

Chew, Michelle S. ^{[1
]}

Puelacher, Christian ^{[2
]}

机构：

[1] Linkoping Univ, Dept Anaesthesia & Intens Care Biomed & Clin Sci, Linkoping, Sweden

[2] Univ Basel, Univ Hosp Basel, Dept Cardiol & Cardiovasc Res Inst Basel, Basel, Switzerland

来源：

CURRENT OPINION IN CRITICAL CARE | 2021年 / 27卷 / 06期

基金：

瑞典研究理事会;

关键词：

major adverse cardiovascular events; myocardial injury after noncardiac surgery; myocardial injury; perioperative; LONG-TERM MORTALITY; TROPONIN-T; INTRAOPERATIVE HYPOTENSION; INFARCTION; ASSOCIATION; PREDICTORS; EVENTS; COHORT;

D O I：

10.1097/MCC.0000000000000885

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Purpose of review Acute myocardial injury occurs commonly during perioperative care. There is still considerable confusion regarding its diagnosis and definition, and a lack of consensus on who and how to screen, exacerbated by a lack of studies addressing how to manage patients with detected myocardial injury. Recent findings Far from a benign biochemical anomaly, myocardial injury occurring perioperatively is largely a silent disease and is not necessarily because of ischaemia. Preoperative, postoperative, and perioperative changes in cardiac troponins (cTns) are independently associated with increased mortality and adverse cardiovascular outcomes. Routine screening with cTns is required for reliable detection of myocardial injury. Measurement of changes (from preoperative to postoperative) will detect acute events as well as identify patients with chronic troponin increases. This review aims to bring together current literature regarding myocardial injury that is detected perioperatively, identifies knowledge gaps for future research and provides suggestions for management.

引用

页码：670 / 675

页数：6

共 29 条

[1] A Prospective International Multicentre Cohort Study of Intraoperative Heart Rate and Systolic Blood Pressure and Myocardial Injury After Noncardiac Surgery: Results of the VISION Study [J].

Abbott, Tom E. F. ;

Pearse, Rupert M. ;

Archbold, R. Andrew ;

Ahmad, Tahania ;

Niebrzegowska, Edyta ;

Wragg, Andrew ;

Rodseth, Reitze N. ;

Devereaux, Philip J. ;

Ackland, Gareth L. .

ANESTHESIA AND ANALGESIA, 2018, 126 (06) :1936-1945

[2] Myocardial Injury after Noncardiac Surgery A Large, International, Prospective Cohort Study Establishing Diagnostic Criteria, Characteristics, Predictors, and 30-day Outcomes [J].

Botto, Fernando ;

Alonso-Coello, Pablo ;

Chan, Matthew T. V. ;

Carlos Villar, Juan ;

Xavier, Denis ;

Srinathan, Sadeesh ;

Guyatt, Gordon ;

Cruz, Patricia ;

Graham, Michelle ;

Wang, C. Y. ;

Berwanger, Otavio ;

Pearse, Rupert M. ;

Biccard, Bruce M. ;

Abraham, Valsa ;

Malaga, German ;

Hillis, Graham S. ;

Rodseth, Reitze N. ;

Cook, Deborah ;

Polanczyk, Carisi A. ;

Szczeklik, Wojciech ;

Sessler, Daniel I. ;

Sheth, Tej ;

Ackland, Gareth L. ;

Leuwer, Martin ;

Garg, Amit X. ;

LeManach, Yannick ;

Pettit, Shirley ;

Heels-Ansdell, Diane ;

LuratiBuse, Giovanna ;

Walsh, Michael ;

Sapsford, Robert ;

Schuenemann, Holger J. ;

Kurz, Andrea ;

Thomas, Sabu ;

Mrkobrada, Marko ;

Thabane, Lehana ;

Gerstein, Hertzel ;

Paniagua, Pilar ;

Nagele, Peter ;

Raina, Parminder ;

Yusuf, Salim ;

Devereaux, P. J. ;

McQueen, Matthew J. ;

Bhandari, Mohit ;

Bosch, Jackie ;

Buckley, Norman ;

Chow, Clara K. ;

Halliwell, Richard ;

Li, Stephen ;

Lee, Vincent W. .

ANESTHESIOLOGY, 2014, 120 (03) :564-578

[3] Pre-operative evaluation of adults undergoing elective noncardiac surgery Updated guideline from the European Society of Anaesthesiology [J].

De Hert, Stefan ;

Staender, Sven ;

Fritsch, Gerhard ;

Hinkelbein, Jochen ;

Afshari, Arash ;

Bettelli, Gabriella ;

Bock, Matthias ;

Chew, Michelle S. ;

Coburn, Mark ;

De Robertis, Edoardo ;

Drinhaus, Hendrik ;

Feldheiser, Aarne ;

Geldner, Gotz ;

Lahner, Daniel ;

Macas, Andrius ;

Neuhaus, Christopher ;

Rauch, Simon ;

Santos-Ampuero, Maria Angeles ;

Solca, Maurizio ;

Tanha, Nima ;

Traskaite, Vilma ;

Wagner, Gernot ;

Wappler, Frank .

EUROPEAN JOURNAL OF ANAESTHESIOLOGY, 2018, 35 (06) :407-465

[4] Effects of extended-release metoprolol succinate inpatients undergoing non-cardiac surgery (POISE trial):: a randomised controlled trial [J].

Devereaux, P. J. ;

Yang, Homer ;

Yusuf, Salim ;

Guyatt, Gordon ;

Leslie, Kate ;

Villar, Juan Carlos ;

Xavier, Denis ;

Chrolavicius, Susan ;

Greenspan, Launi ;

Pogue, Janice ;

Pais, Prem ;

Liu, Lisheng ;

Xu, Shouchun ;

Malaga, German ;

Avezum, Alvaro ;

Chan, Matthew ;

Montori, Victor M. ;

Jacka, Mike ;

Choi, Peter .

LANCET, 2008, 371 (9627) :1839-1847

[5] Dabigatran in patients with myocardial injury after non-cardiac surgery (MANAGE): an international, randomised, placebo-controlled trial [J].

Devereaux, P. J. ;

Duceppe, Emmanuelle ;

Guyatt, Gordon ;

Tandon, Vikas ;

Rodseth, Reitze ;

Biccard, Bruce M. ;

Xavier, Denis ;

Szczeklik, Wojciech ;

Meyhoff, Christian S. ;

Vincent, Jessica ;

Franzosi, Maria Grazia ;

Srinathan, Sadeesh K. ;

Erb, Jason ;

Magloire, Patrick ;

Neary, John ;

Rao, Mangala ;

Rahate, Prashant V. ;

Chaudhry, Navneet K. ;

Mayosi, Bongani ;

de Nadal, Miriam ;

Iglesias, Pilar Paniagua ;

Berwanger, Otavio ;

Villar, Juan Carlos ;

Botto, Fernando ;

Eikelboom, John W. ;

Sessler, Daniel I. ;

Kearon, Clive ;

Pettit, Shirley ;

Sharma, Mukul ;

Connolly, Stuart J. ;

Bangdiwala, Shrikant I. ;

Rao-Melacini, Purnima ;

Hoeft, Andreas ;

Yusuf, Salim .

LANCET, 2018, 391 (10137) :2325-2334

[6] Association of Postoperative High-Sensitivity Troponin Levels With Myocardial Injury and 30-Day Mortality Among Patients Undergoing Noncardiac Surgery [J].

Devereaux, P. J. ;

Biccard, Bruce M. ;

Sigamani, Alben ;

Xavier, Denis ;

Chan, Matthew T. V. ;

Srinathan, Sadeesh K. ;

Walsh, Michael ;

Abraham, Valsa ;

Pearse, Rupert ;

Wang, C. Y. ;

Sessler, Daniel I. ;

Kurz, Andrea ;

Szczeklik, Wojciech ;

Berwanger, Otavio ;

Carlos Villar, Juan ;

Malaga, German ;

Garg, Amit X. ;

Chow, Clara K. ;

Ackland, Gareth ;

Patel, Ameen ;

Borges, Flavia Kessler ;

Belley-Cote, Emilie P. ;

Duceppe, Emmanuelle ;

Spence, Jessica ;

Tandon, Vikas ;

Williams, Colin ;

Sapsford, Robert J. ;

Polanczyk, Carisi A. ;

Tiboni, Maria ;

Alonso-Coello, Pablo ;

Faruqui, Atiya ;

Heels-Ansdell, Diane ;

Lamy, Andre ;

Whitlock, Richard ;

LeManach, Yannick ;

Roshanov, Pavel S. ;

McGillion, Michael ;

Kavsak, Peter ;

McQueen, Matthew J. ;

Thabane, Lehana ;

Rodseth, Reitze N. ;

Buse, Giovanna A. Lurati ;

Bhandari, Mohit ;

Garutti, Ignacia ;

Jacka, Michael J. ;

Schuenemann, Holger J. ;

Lucia Cortes, Olga ;

Coriat, Pierre ;

Dvirnik, Nazari ;

Botto, Fernando .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2017, 317 (16) :1642-1651

[7] Clonidine in Patients Undergoing Noncardiac Surgery [J].

Devereaux, P. J. ;

Sessler, D. I. ;

Leslie, K. ;

Kurz, A. ;

Mrkobrada, M. ;

Alonso-Coello, P. ;

Villar, J. C. ;

Sigamani, A. ;

Biccard, B. M. ;

Meyhoff, C. S. ;

Parlow, J. L. ;

Guyatt, G. ;

Robinson, A. ;

Garg, A. X. ;

Rodseth, R. N. ;

Botto, F. ;

Buse, G. Lurati ;

Xavier, D. ;

Chan, M. T. V. ;

Tiboni, M. ;

Cook, D. ;

Kumar, P. A. ;

Forget, P. ;

Malaga, G. ;

Fleischmann, E. ;

Amir, M. ;

Eikelboom, J. ;

Mizera, R. ;

Torres, D. ;

Wang, C. Y. ;

VanHelder, T. ;

Paniagua, P. ;

Berwanger, O. ;

Srinathan, S. ;

Graham, M. ;

Pasin, L. ;

Le Manach, Y. ;

Gao, P. ;

Pogue, J. ;

Whitlock, R. ;

Lamy, A. ;

Kearon, C. ;

Chow, C. ;

Pettit, S. ;

Chrolavicius, S. ;

Yusuf, S. .

NEW ENGLAND JOURNAL OF MEDICINE, 2014, 370 (16) :1504-1513

[8] Aspirin in Patients Undergoing Noncardiac Surgery [J].

Devereaux, P. J. ;

Mrkobrada, M. ;

Sessler, D. I. ;

Leslie, K. ;

Alonso-Coello, P. ;

Kurz, A. ;

Villar, J. C. ;

Sigamani, A. ;

Biccard, B. M. ;

Meyhoff, C. S. ;

Parlow, J. L. ;

Guyatt, G. ;

Robinson, A. ;

Garg, A. X. ;

Rodseth, R. N. ;

Botto, F. ;

Buse, G. Lurati ;

Xavier, D. ;

Chan, M. T. V. ;

Tiboni, M. ;

Cook, D. ;

Kumar, P. A. ;

Forget, P. ;

Malaga, G. ;

Fleischmann, E. ;

Amir, M. ;

Eikelboom, J. ;

Mizera, R. ;

Torres, D. ;

Wang, C. Y. ;

VanHelder, T. ;

Paniagua, P. ;

Berwanger, O. ;

Srinathan, S. ;

Graham, M. ;

Pasin, L. ;

Le Manach, Y. ;

Gao, P. ;

Pogue, J. ;

Whitlock, R. ;

Lamy, A. ;

Kearon, C. ;

Baigent, C. ;

Chow, C. ;

Pettit, S. ;

Chrolavicius, S. ;

Yusuf, S. .

NEW ENGLAND JOURNAL OF MEDICINE, 2014, 370 (16) :1494-1503

[9] Characteristics and Short- Term Prognosis of Perioperative Myocardial Infarction in Patients Undergoing Noncardiac Surgery A Cohort Study [J].

Devereaux, P. J. ;

Xavier, Denis ;

Pogue, Janice ;

Guyatt, Gordon ;

Sigamani, Alben ;

Garutti, Ignacio ;

Leslie, Kate ;

Rao-Melacini, Purnima ;

Chrolavicius, Sue ;

Yang, Homer ;

MacDonald, Colin ;

Avezum, Alvaro ;

Lanthier, Luc ;

Hu, Weijiang ;

Yusuf, Salim .

ANNALS OF INTERNAL MEDICINE, 2011, 154 (08) :523-528

[10] Canadian Cardiovascular Society Guidelines on Perioperative Cardiac Risk Assessment and Management for Patients Who Undergo Noncardiac Surgery [J].

Duceppe, Emmanuelle ;

Parlow, Joel ;

MacDonald, Paul ;

Lyons, Kristin ;

McMullen, Michael ;

Srinathan, Sadeesh ;

Graham, Michelle ;

Tandon, Vikas ;

Styles, Kim ;

Bessissow, Amal ;

Sessler, Daniel I. ;

Bryson, Gregory ;

Devereaux, P. J. .

CANADIAN JOURNAL OF CARDIOLOGY, 2017, 33 (01) :17-32

← 1 2 3 →

共 29 条

[1] A Prospective International Multicentre Cohort Study of Intraoperative Heart Rate and Systolic Blood Pressure and Myocardial Injury After Noncardiac Surgery: Results of the VISION Study [J].

Abbott, Tom E. F. ;

Pearse, Rupert M. ;

Archbold, R. Andrew ;

Ahmad, Tahania ;

Niebrzegowska, Edyta ;

Wragg, Andrew ;

Rodseth, Reitze N. ;

Devereaux, Philip J. ;

Ackland, Gareth L. .

ANESTHESIA AND ANALGESIA, 2018, 126 (06) :1936-1945

[2] Myocardial Injury after Noncardiac Surgery A Large, International, Prospective Cohort Study Establishing Diagnostic Criteria, Characteristics, Predictors, and 30-day Outcomes [J].

Botto, Fernando ;

Alonso-Coello, Pablo ;

Chan, Matthew T. V. ;

Carlos Villar, Juan ;

Xavier, Denis ;

Srinathan, Sadeesh ;

Guyatt, Gordon ;

Cruz, Patricia ;

Graham, Michelle ;

Wang, C. Y. ;

Berwanger, Otavio ;

Pearse, Rupert M. ;

Biccard, Bruce M. ;

Abraham, Valsa ;

Malaga, German ;

Hillis, Graham S. ;

Rodseth, Reitze N. ;

Cook, Deborah ;

Polanczyk, Carisi A. ;

Szczeklik, Wojciech ;

Sessler, Daniel I. ;

Sheth, Tej ;

Ackland, Gareth L. ;

Leuwer, Martin ;

Garg, Amit X. ;

LeManach, Yannick ;

Pettit, Shirley ;

Heels-Ansdell, Diane ;

LuratiBuse, Giovanna ;

Walsh, Michael ;

Sapsford, Robert ;

Schuenemann, Holger J. ;

Kurz, Andrea ;

Thomas, Sabu ;

Mrkobrada, Marko ;

Thabane, Lehana ;

Gerstein, Hertzel ;

Paniagua, Pilar ;

Nagele, Peter ;

Raina, Parminder ;

Yusuf, Salim ;

Devereaux, P. J. ;

McQueen, Matthew J. ;

Bhandari, Mohit ;

Bosch, Jackie ;

Buckley, Norman ;

Chow, Clara K. ;

Halliwell, Richard ;

Li, Stephen ;

Lee, Vincent W. .

ANESTHESIOLOGY, 2014, 120 (03) :564-578

[3] Pre-operative evaluation of adults undergoing elective noncardiac surgery Updated guideline from the European Society of Anaesthesiology [J].

De Hert, Stefan ;

Staender, Sven ;

Fritsch, Gerhard ;

Hinkelbein, Jochen ;

Afshari, Arash ;

Bettelli, Gabriella ;

Bock, Matthias ;

Chew, Michelle S. ;

Coburn, Mark ;

De Robertis, Edoardo ;

Drinhaus, Hendrik ;

Feldheiser, Aarne ;

Geldner, Gotz ;

Lahner, Daniel ;

Macas, Andrius ;

Neuhaus, Christopher ;

Rauch, Simon ;

Santos-Ampuero, Maria Angeles ;

Solca, Maurizio ;

Tanha, Nima ;

Traskaite, Vilma ;

Wagner, Gernot ;

Wappler, Frank .

EUROPEAN JOURNAL OF ANAESTHESIOLOGY, 2018, 35 (06) :407-465

[4] Effects of extended-release metoprolol succinate inpatients undergoing non-cardiac surgery (POISE trial):: a randomised controlled trial [J].

Devereaux, P. J. ;

Yang, Homer ;

Yusuf, Salim ;

Guyatt, Gordon ;

Leslie, Kate ;

Villar, Juan Carlos ;

Xavier, Denis ;

Chrolavicius, Susan ;

Greenspan, Launi ;

Pogue, Janice ;

Pais, Prem ;

Liu, Lisheng ;

Xu, Shouchun ;

Malaga, German ;

Avezum, Alvaro ;

Chan, Matthew ;

Montori, Victor M. ;

Jacka, Mike ;

Choi, Peter .

LANCET, 2008, 371 (9627) :1839-1847

[5] Dabigatran in patients with myocardial injury after non-cardiac surgery (MANAGE): an international, randomised, placebo-controlled trial [J].

Devereaux, P. J. ;

Duceppe, Emmanuelle ;

Guyatt, Gordon ;

Tandon, Vikas ;

Rodseth, Reitze ;

Biccard, Bruce M. ;

Xavier, Denis ;

Szczeklik, Wojciech ;

Meyhoff, Christian S. ;

Vincent, Jessica ;

Franzosi, Maria Grazia ;

Srinathan, Sadeesh K. ;

Erb, Jason ;

Magloire, Patrick ;

Neary, John ;

Rao, Mangala ;

Rahate, Prashant V. ;

Chaudhry, Navneet K. ;

Mayosi, Bongani ;

de Nadal, Miriam ;

Iglesias, Pilar Paniagua ;

Berwanger, Otavio ;

Villar, Juan Carlos ;

Botto, Fernando ;

Eikelboom, John W. ;

Sessler, Daniel I. ;

Kearon, Clive ;

Pettit, Shirley ;

Sharma, Mukul ;

Connolly, Stuart J. ;

Bangdiwala, Shrikant I. ;

Rao-Melacini, Purnima ;

Hoeft, Andreas ;

Yusuf, Salim .

LANCET, 2018, 391 (10137) :2325-2334

[6] Association of Postoperative High-Sensitivity Troponin Levels With Myocardial Injury and 30-Day Mortality Among Patients Undergoing Noncardiac Surgery [J].

Devereaux, P. J. ;

Biccard, Bruce M. ;

Sigamani, Alben ;

Xavier, Denis ;

Chan, Matthew T. V. ;

Srinathan, Sadeesh K. ;

Walsh, Michael ;

Abraham, Valsa ;

Pearse, Rupert ;

Wang, C. Y. ;

Sessler, Daniel I. ;

Kurz, Andrea ;

Szczeklik, Wojciech ;

Berwanger, Otavio ;

Carlos Villar, Juan ;

Malaga, German ;

Garg, Amit X. ;

Chow, Clara K. ;

Ackland, Gareth ;

Patel, Ameen ;

Borges, Flavia Kessler ;

Belley-Cote, Emilie P. ;

Duceppe, Emmanuelle ;

Spence, Jessica ;

Tandon, Vikas ;

Williams, Colin ;

Sapsford, Robert J. ;

Polanczyk, Carisi A. ;

Tiboni, Maria ;

Alonso-Coello, Pablo ;

Faruqui, Atiya ;

Heels-Ansdell, Diane ;

Lamy, Andre ;

Whitlock, Richard ;

LeManach, Yannick ;

Roshanov, Pavel S. ;

McGillion, Michael ;

Kavsak, Peter ;

McQueen, Matthew J. ;

Thabane, Lehana ;

Rodseth, Reitze N. ;

Buse, Giovanna A. Lurati ;

Bhandari, Mohit ;

Garutti, Ignacia ;

Jacka, Michael J. ;

Schuenemann, Holger J. ;

Lucia Cortes, Olga ;

Coriat, Pierre ;

Dvirnik, Nazari ;

Botto, Fernando .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2017, 317 (16) :1642-1651

[7] Clonidine in Patients Undergoing Noncardiac Surgery [J].

Devereaux, P. J. ;

Sessler, D. I. ;

Leslie, K. ;

Kurz, A. ;

Mrkobrada, M. ;

Alonso-Coello, P. ;

Villar, J. C. ;

Sigamani, A. ;

Biccard, B. M. ;

Meyhoff, C. S. ;

Parlow, J. L. ;

Guyatt, G. ;

Robinson, A. ;

Garg, A. X. ;

Rodseth, R. N. ;

Botto, F. ;

Buse, G. Lurati ;

Xavier, D. ;

Chan, M. T. V. ;

Tiboni, M. ;

Cook, D. ;

Kumar, P. A. ;

Forget, P. ;

Malaga, G. ;

Fleischmann, E. ;

Amir, M. ;

Eikelboom, J. ;

Mizera, R. ;

Torres, D. ;

Wang, C. Y. ;

VanHelder, T. ;

Paniagua, P. ;

Berwanger, O. ;

Srinathan, S. ;

Graham, M. ;

Pasin, L. ;

Le Manach, Y. ;

Gao, P. ;

Pogue, J. ;

Whitlock, R. ;

Lamy, A. ;

Kearon, C. ;

Chow, C. ;

Pettit, S. ;

Chrolavicius, S. ;

Yusuf, S. .

NEW ENGLAND JOURNAL OF MEDICINE, 2014, 370 (16) :1504-1513

[8] Aspirin in Patients Undergoing Noncardiac Surgery [J].

Devereaux, P. J. ;

Mrkobrada, M. ;

Sessler, D. I. ;

Leslie, K. ;

Alonso-Coello, P. ;

Kurz, A. ;

Villar, J. C. ;

Sigamani, A. ;

Biccard, B. M. ;

Meyhoff, C. S. ;

Parlow, J. L. ;

Guyatt, G. ;

Robinson, A. ;

Garg, A. X. ;

Rodseth, R. N. ;

Botto, F. ;

Buse, G. Lurati ;

Xavier, D. ;

Chan, M. T. V. ;

Tiboni, M. ;

Cook, D. ;

Kumar, P. A. ;

Forget, P. ;

Malaga, G. ;

Fleischmann, E. ;

Amir, M. ;

Eikelboom, J. ;

Mizera, R. ;

Torres, D. ;

Wang, C. Y. ;

VanHelder, T. ;

Paniagua, P. ;

Berwanger, O. ;

Srinathan, S. ;

Graham, M. ;

Pasin, L. ;

Le Manach, Y. ;

Gao, P. ;

Pogue, J. ;

Whitlock, R. ;

Lamy, A. ;

Kearon, C. ;

Baigent, C. ;

Chow, C. ;

Pettit, S. ;

Chrolavicius, S. ;

Yusuf, S. .

NEW ENGLAND JOURNAL OF MEDICINE, 2014, 370 (16) :1494-1503

[9] Characteristics and Short- Term Prognosis of Perioperative Myocardial Infarction in Patients Undergoing Noncardiac Surgery A Cohort Study [J].

Devereaux, P. J. ;

Xavier, Denis ;

Pogue, Janice ;

Guyatt, Gordon ;

Sigamani, Alben ;

Garutti, Ignacio ;

Leslie, Kate ;

Rao-Melacini, Purnima ;

Chrolavicius, Sue ;

Yang, Homer ;

MacDonald, Colin ;

Avezum, Alvaro ;

Lanthier, Luc ;

Hu, Weijiang ;

Yusuf, Salim .

ANNALS OF INTERNAL MEDICINE, 2011, 154 (08) :523-528

[10] Canadian Cardiovascular Society Guidelines on Perioperative Cardiac Risk Assessment and Management for Patients Who Undergo Noncardiac Surgery [J].

Duceppe, Emmanuelle ;

Parlow, Joel ;

MacDonald, Paul ;

Lyons, Kristin ;

McMullen, Michael ;

Srinathan, Sadeesh ;

Graham, Michelle ;

Tandon, Vikas ;

Styles, Kim ;

Bessissow, Amal ;

Sessler, Daniel I. ;

Bryson, Gregory ;

Devereaux, P. J. .

CANADIAN JOURNAL OF CARDIOLOGY, 2017, 33 (01) :17-32

← 1 2 3 →