Rhodium-Catalyzed Anti-Markovnikov Hydroamination of Aliphatic and Aromatic Terminal Alkynes with Aliphatic Primary Amines

被引：8

作者：

Morimoto, Yoshihiko ^{[1
]}

Kochi, Takuya ^{[1
]}

Kakiuchi, Fumitoshi ^{[1
]}

机构：

[1] Keio Univ, Fac Sci & Technol, Dept Chem, Yokohama, Kanagawa 2238522, Japan

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2021年 / 86卷 / 18期

关键词：

INTERMOLECULAR HYDROAMINATION; SECONDARY-AMINES; CYCLOPENTADIENYL LIGAND; GENERAL CATALYST; PENDANT ETHER; COMPLEXES; SUBSTITUENT; ARYLACETYLENES; ALCOHOLS; BEHAVIOR;

D O I：

10.1021/acs.joc.1c01636

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Anti-Markovnikov hydroamination of both aliphatic and aromatic terminal alkynes with primary amines was achieved using an 8-quinolinolato rhodium catalyst to form aldimines and enamines in high yields. This catalytic system realized high functional group tolerance including hydroxy, bromo, cyano, and thioester groups.

引用

页码：13143 / 13152

页数：10

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