Oxidative stress and female reproductive disorder: A review

被引:15
作者
Manokaran, Kalaivani [1 ]
Bhat, Pavithra [1 ]
Nayak, Deepak [2 ]
Baskaran, Ravisankar [3 ]
Paramasivam, Prabu [4 ]
Ahmed, Shiek Fareeth [5 ]
Priya, Keerthi [6 ]
Pai, Karkala Sreedhara Ranganath [6 ]
Balaji, Vignesh E. [6 ]
机构
[1] Manipal Acad Higher Educ, Manipal Coll Hlth Prof, Dept Med Lab Technol, Manipal 576104, India
[2] Manipal Acad Higher Educ, Kasturba Med Coll, Dept Pathol, Manipal 576104, India
[3] Univ Madras, Dr ALM PGIBMS, Dept Endocrinol, Chennai, Tamil Nadu, India
[4] Univ New Mexico, Univ New Mexico Hlth Sci Ctr, Dept Neurol, Sch Med, Albuquerque, NM 87131 USA
[5] Chettinad Hosp & Res Inst, Fac Allied Hlth Sci, Chennai 603103, Tamil Nadu, India
[6] Manipal Acad Higher Educ, Dept Pharmacol, Manipal Coll Pharmaceut Sci, Manipal 576104, India
关键词
POLYCYSTIC-OVARY-SYNDROME; VITAMIN-E SUPPLEMENTATION; INSULIN-RESISTANCE; ASCORBIC-ACID; FOLLICULAR-FLUID; FREE-RADICALS; LUTEAL-PHASE; VASCULAR DYSFUNCTION; SERUM MARKERS; WOMEN;
D O I
10.4103/2305-0500.346088
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Oxidative stress arises from an imbalance between the body's pro-oxidants and antioxidants. Recently, oxidative stress has been proven a contributing factor to many female reproductive disorders including infertility, preeclampsia, endometriosis and polycystic ovarian syndrome. Herein, we review the mechanistic role of oxidative stress in inducing the most common female reproductive disorders. The current review has also highlighted the protective role of vitamin C, necessary for certain female reproductive hormone secretion by the antral follicle and corpus luteum and also essential for collagen production in ovarian tissue remodeling after ovulation, in alleviating oxidative stress and thus improving female reproductive outcomes.
引用
收藏
页码:107 / 116
页数:10
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