Microfluidic glass chips with an integrated nanospray emitter for coupling to a mass spectrometer

被引:88
作者
Hoffmann, Peter
Haeusig, Ulrich
Schulze, Philipp
Belder, Detlev [1 ]
机构
[1] Univ Regensburg, Inst Analyt Chem Chemo & Biosensor, D-93040 Regensburg, Germany
[2] Max Planck Inst Kohlenforsch, D-45470 Mulheim, Germany
关键词
electrophoresis; lab-on-a-chip; mass spectrometry; microfluidics; nanospray;
D O I
10.1002/anie.200605152
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
(Figure Presented) A coupling coup: A novel microfluidic chip with an integrated nanospray emitter enables the first dead-volume-free coupling of glass-chip laboratories with mass spectrometry. An electrophoretic version of the system may be suitable for the separation and analysis of drugs, for example, and has potential for the high-throughput analysis of miniscule amounts of samples. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:4913 / 4916
页数:4
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