Challenges of probe cocktail approach for human drug-drug interaction assays

被引：3
|
作者：
Carrao, Daniel B. [1 ]
de Oliveira, Anderson R. M. [1 ]
Magalhaes, Igor R. S. [2 ]
机构：
[1] Univ Sao Paulo, FFCLRP, Dept Quim, Lab Metab Vitro & Tecn Separacao, BR-14040901 Ribeirao Preto, Brazil
[2] Univ Fed Amazonas, UFAM, FCF, Nucleo Estudos Farmacocinet, BR-69077000 Manaus, Amazonas, Brazil
来源：
BIOANALYSIS | 2018年 / 10卷 / 24期
基金：
巴西圣保罗研究基金会;
关键词：
CYP450; drug-drug interaction; HLM; in vitro models; mass spectrometry; N-in-one; probe cocktail; HUMAN LIVER-MICROSOMES; IN-VITRO COCKTAIL; LIQUID-CHROMATOGRAPHY; CYTOCHROME-P450; ASSAY; INHIBITION; ENZYMES; VALIDATION;
D O I：
10.4155/bio-2018-0247
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
[No abstract available]
引用
收藏
页码：1969 / 1972
页数：4
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