[1] Univ Basel Hosp, Neurol Clin & Policlin, Dept Med, Basel, Switzerland
[2] Univ Basel Hosp, Neurol Clin & Policlin, Dept Clin Res, Basel, Switzerland
[3] Univ Basel Hosp, Neurol Clin & Policlin, Dept Biomed, Basel, Switzerland
[4] Univ Basel Hosp, Neurol Clin & Policlin, Dept Biomed Engn, Basel, Switzerland
[5] Univ Siena, Siena, Italy
[6] Univ Genoa, Dept Hlth Sci, Biostat Unit, Genoa, Italy
[7] Queen Mary Univ London, Barts & London Sch Med & Dent, Blizard Inst, London, England
[8] Novartis Pharma AG, Basel, Switzerland
[9] Massachusetts Gen Hosp, Partners Pediat Multiple Sclerosis Ctr, Boston, MA 02114 USA