Enantioselective organocatalytic transfer hydrogenation reactions using Hantzsch esters

被引：466

作者：

Ouellet, Stephane G. ^{[2
]}

Walji, Abbas M. ^{[1
]}

Macmillan, David W. C. ^{[1
]}

机构：

[1] Princeton Univ, Merck Ctr Catalysis, Princeton, NJ 08544 USA

[2] Merck Frosst Ctr Therapeut Res, Dept Proc Res, Kirkland, PQ H9H 3L1, Canada

来源：

ACCOUNTS OF CHEMICAL RESEARCH | 2007年 / 40卷 / 12期

关键词：

D O I：

10.1021/ar7001864

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Within the realm of catalytic asymmetric hydrogenation, the focus continues to be on the use of chiral metal complexes in conjunction with a hydrogen Source. Recently, the widespread development of organocatalysis, including the invention of iminium activation, has led to the discovery of many new enantioselective transformations. Based on this strategy, a number of bioinspired processes for the enantioselective organocatalytic transfer hydrogenation of alpha,beta-unsaturated carbonyl Compounds and imines have been discovered. These topics will be the focus of this Account.

引用

页码：1327 / 1339

页数：13

共 51 条

[31] McMurry J., 2005, ORGANIC CHEM BIOL PA
[32] NAD(P)H MODELS .20. CHEMOSELECTIVE METAL-ION CATALYZED REDUCTION OF ALPHA-KETO-BETA,GAMMA-UNSATURATED ESTERS BY 1,4-DIHYDROPYRIDINE DERIVATIVES
MEIJER, LHP
PANDIT, UK
[J]. TETRAHEDRON, 1985, 41 (02) : 467 - 472
[33] SYNTHESIS OF 2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL (BINAP), AN ATROPISOMERIC CHIRAL BIS(TRIARYL)PHOSPHINE, AND ITS USE IN THE RHODIUM(I)-CATALYZED ASYMMETRIC HYDROGENATION OF ALPHA-(ACYLAMINO)ACRYLIC ACIDS
MIYASHITA, A
YASUDA, A
TAKAYA, H
TORIUMI, K
ITO, T
SOUCHI, T
NOYORI, R
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1980, 102 (27) : 7932 - 7934
[34] The first general enantioselective catalytic Diels-Alder reaction with simple α,β-unsaturated ketones
Northrup, AB
MacMillan, DWC
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (11) : 2458 - 2460
[35] Chiral proton catalysis: A catalytic enantioselective direct aza-Henry reaction
Nugent, BM
Yoder, RA
Johnston, JN
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (11) : 3418 - 3419
[36] Ohkuma T., 2000, CATALYTIC ASYMMETRIC, P1
[37] Ohkuma T., 1999, COMPREHENSIVE ASYMME, V1
[38] Enantioselective Aza-Henry reaction catalyzed by a bifunctional organocatalyst
Okino, T
Nakamura, S
Furukawa, T
Takemoto, Y
[J]. ORGANIC LETTERS, 2004, 6 (04) : 625 - 627
[39] Enantioselective organocatalytic hydride reduction
Ouellet, SG
Tuttle, JB
MacMillan, DWC
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (01) : 32 - 33
[40] New strategies in organic catalysis: The first enantioselective organocatalytic Friedel-Crafts alkylation
Paras, NA
MacMillan, DWC
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (18) : 4370 - 4371

← 1 2 3 4 5 6 →