Late-onset interface inflammation associated with wearing cosmetic lenses 18 months after laser in situ keratomileusis

Purpose: To report a case of late-onset interface inflammation associated with wearing a cosmetic lens 18 months after laser in situ keratomileusis (LASIK). Methods: A 25-year-old woman visited our hospital with visual disturbance and ocular pain in the left eye. The patient had undergone LASIK in both eyes 18 months ago and had been wearing cosmetic lenses intermittently for 6 months. The day before presentation, the patient had slept with cosmetic lenses. At presentation, best-corrected visual acuity was 2/200 in the left eye. Slit-lamp examination of the left eye revealed corneal edema and a diffuse granular white infiltrate at the interface. Results: Intense topical steroid and antibiotic treatment resulted in resolution of interface inflammation. After 2 weeks, the corneal infiltrate had resolved, and best-corrected visual acuity had improved to 20/25. Conclusions: This case indicates that late-onset interface inflammation can develop in association with the use of cosmetic lenses in LASIK-treated eyes.