Control of chitosan molecular weight with cyclotron ion beam irradiation

被引：7

作者：

Kim, Mi-Sook ^{[1
]}

Choi, Yoon-Jeong ^{[1
]}

Noh, Insup ^{[1
]}

机构：

[1] Seoul Natl Univ Technol, Dept Chem Engn, Ecoprod & Mat Educ Ctr, Seoul 139743, South Korea

来源：

JOURNAL OF PHYSICS AND CHEMISTRY OF SOLIDS | 2008年 / 69卷 / 5-6期

关键词：

polymers; chemical synthesis; surface properties;

D O I：

10.1016/j.jpcs.2007.10.039

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Control of water-soluble chitosan molecular weight was performed by irradiation of cyclotron proton ion beams by changing treatment conditions such as beam irradiation time for upto 10 min, beam energies as well as beam distances between the sample surface and beam after pre-calculating the sample positions with Stopping and Range of Ions in Matter software. Irradiation of high energy cyclotron ion beam induced significant reduction of molecular weights of water-soluble chitosan as observed by changes in both relative viscosity and molecular weights measured by gel permeation chromatography. The molecular weights of the beam-treated chitosan were reduced to 55-20% compared to that of the untreated one, depending on the beam irradiation conditions such as treatment time and beam energy. Polydispersity index indicated that the reduced chitosan molecular weights were wider distributed compared to that of the untreated chitosan samples. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：1577 / 1580

页数：4

共 4 条

[1]

KIM GW, 2005, J CHITIN CHITOSAN, V10, P128

[2] Bone regeneration using hyaluronic acid-based hydrogel with bone morphogenic protein-2 and human mesenchymal stem cells [J].

Kim, Jungju ;

Kim, In Sook ;

Cho, Tae Hyung ;

Lee, Kyu Back ;

Hwang, Soon Jung ;

Tae, Giyoong ;

Noh, Insup ;

Lee, Sang Hoon ;

Park, Yongdoo ;

Sun, Kyung .

BIOMATERIALS, 2007, 28 (10) :1830-1837

[3]

NOH I, 2007, MAT RES A, V83, P674

[4] The enzymatic degradation and swelling properties of chitosan matrices with different degrees of N-acetylation [J].

Ren, DW ;

Yi, HF ;

Wang, W ;

Ma, XJ .

CARBOHYDRATE RESEARCH, 2005, 340 (15) :2403-2410

← 1 →