Highly selective, naked-eye and fluorescent "off-on" probe for detection of histidine/histidine-rich proteins and its application in living cell imaging

被引:21
作者
Zhang, Shenyi [1 ]
Yang, Chunmei [1 ]
Zhu, Weiping [1 ]
Zeng, Bubing [1 ]
Yang, Youjun [1 ]
Xu, Yufang [1 ]
Qian, Xuhong [1 ]
机构
[1] E China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai Key Lab Chem Biol, Sch Pharm, Shanghai 200237, Peoples R China
基金
国家高技术研究发展计划(863计划); 中国国家自然科学基金;
关键词
AMINO-ACIDS; HISTIDINE; SENSOR; CHEMOSENSOR; PLASMA; ENSEMBLE; COMPLEX; SILVER;
D O I
10.1039/c2ob06520g
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A highly selective colorimetric and fluorescence enhanced probe S1 (M2@Cu) for histidine and histidine-rich proteins has been developed. In neutral aqueous ethanol solution, probe S1 can selectively detect histidine out of twenty DNA encoded amino acids by showing a color change from brownish red to light green, and with a fluorescence enhancement up to 99-fold at 537 nm, simultaneously.
引用
收藏
页码:1653 / 1658
页数:6
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